Observational studyThe British journal of surgery2023
Early outcomes from the Minimally Invasive Right Colectomy Anastomosis study (MIRCAST).
Observational study in The British journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Minimally Invasive Surgery for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Robotic Versus Laparoscopic Surgical Techniques.Journal of Crohn's & colitis · 2024Pooled it
- Robotic versus laparoscopic right hemicolectomy: a systematic review of the evidence.Journal of robotic surgery · 2024Pooled it
- RoLaCaRT-1: pilot randomised phase II study of robotic vs laparoscopic hemicolectomy for right colon cancer.Surgical endoscopy · 2026Trial
- Short-term outcomes for intracorporeal vs. extracorporeal anastomosis in laparoscopic right hemicolectomy for colonic cancer-a prospective cohort study (ICEA-study).International journal of colorectal disease · 2025Trial
- Gastrointestinal functions after laparoscopic right colectomy with intracorporeal anastomosis: a pilot randomized clinical trial on effects of abdominal drain, prolonged antibiotic prophylaxis, and D3 lymphadenectomy with complete mesocolic excision.International journal of colorectal disease · 2024Trial
- Factors influencing surgical difficulty in minimally invasive right hemicolectomy.Surgery today · 2026Article
- Colorectal Cancer Surgery: Laparoscopic vs. Robotic Approaches-A Review of the Literature.Journal of clinical medicine · 2026Review
- Transition to total robotic colorectal practice: feasibility and outcomes in a UK colorectal unit.Journal of robotic surgery · 2026Article
- Surgeons' practices and preferences for performing right hemicolectomy for colorectal cancer: results from the SuPrHem survey.Updates in surgery · 2026Article
- Early outcomes after adopting robotic intracorporeal anastomosis for right hemicolectomy - a propensity-weighted analysis.Journal of robotic surgery · 2026Article
- Article
- Intracorporeal vs extracorporeal anastomosis in laparoscopic right colectomy for colon cancer: a prospective multicenter cohort study (the Hemi-D-TREND study).Surgical endoscopy · 2026Article
- Benchmarking to validate the implementation of a robotic colorectal cancer surgery program. Proposal for a new method to createbenchmarks.Journal of robotic surgery · 2025Observational
- Relationship between anastomotic technique, incisional hernia, and quality of life-the Minimally Invasive Right Colectomy Anastomosis STudy (MIRCAST).The British journal of surgery · 2025Article
- Global benchmarks for minimally invasive right hemicolectomy for cancer.The British journal of surgery · 2025Article
- International expert consensus on a structured approach to robotic multiport right hemicolectomy with complete mesocolic excision and intracorporeal anastomosis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- Improved outcomes with cyanoacrylate glue for ileocolic anastomosis in right colectomy: a multicenter study.Annals of coloproctology · 2025Article
- Current Evidence in Robotic Colorectal Surgery.Cancers · 2025Review
- Stapled versus handsewn closure of enterotomy for intracorporeal overlap anastomosis in laparoscopic colectomy: in vitro study.Techniques in coloproctology · 2025Article
- Risk factors for 30-day unplanned readmissions after surgical procedures in the elderly population.Patient safety in surgery · 2025Article
Corrections and comments
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- Erratum issued
Authors and funding
9 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundThe impact of method of anastomosis and minimally invasive surgical technique on surgical and clinical outcomes after right hemicolectomy is uncertain. The aim of the MIRCAST study was to compare intracorporeal and extracorporeal anastomosis (ICA and ECA respectively), each using either a laparoscopic approach or robot-assisted surgery during right hemicolectomies for benign or malignant tumours.
methodsThis was an international, multicentre, prospective, observational, monitored, non-randomized, parallel, four-cohort study (laparoscopic ECA; laparoscopic ICA; robot-assisted ECA; robot-assisted ICA). High-volume surgeons (at least 30 minimally invasive right colectomy procedures/year) from 59 hospitals across 12 European countries treated patients over a 3-year interval The primary composite endpoint was 30-day success, defined by two measures of efficacy-absence of surgical wound infection and of any major complication within the first 30 days after surgery. Secondary outcomes were: overall complications, conversion rate, duration of operation, and number of lymph nodes harvested. Propensity score analysis was used for comparison of ICA with ECA, and robot-assisted surgery with laparoscopy.
resultsSome 1320 patients were included in an intention-to-treat analysis (laparoscopic ECA, 555; laparoscopic ICA, 356; robot-assisted ECA, 88; robot-assisted ICA, 321). No differences in the co-primary endpoint at 30 days after surgery were observed between cohorts (7.2 and 7.6 per cent in ECA and ICA groups respectively; 7.8 and 6.6 per cent in laparoscopic and robot-assisted groups). Lower overall complication rates were observed after ICA, specifically less ileus, and nausea and vomiting after robot-assisted procedures.
conclusionNo difference in the composite outcome of surgical wound infections and severe postoperative complications was found between intracorporeal versus extracorporeal anastomosis or laparoscopy versus robot-assisted surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.