Evidence map›Paper›PMID 37289904›Full record

ReviewCirculation research2023

Molecular Biomarkers for Cardiometabolic Disease: Risk Assessment in Young Individuals.

Usman A Tahir, Robert E Gerszten

Open access · greenAbstract readReview
In one paragraph

Review in Circulation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Usman A TahirDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School.
Robert E GersztenDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School.ORCID 0000-0002-6767-7687
Beth Israel Deaconess Medical Center · US

Funding

Preterm Birth, Maternal and Cord Blood Metabolome, and Child Metabolic RiskR01HD041702 · NICHD · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI Frank B Hu, XIAOBIN WANG · 2001 to 2026
$11.1M
Metabolomic predictors of insulin resistance and diabetesR01DK081572 · NIDDK · VANDERBILT UNIVERSITY · PI CLISH, CLARY B, GERSZTEN, ROBERT E · 2008 to 2025
$9.3M
Proteomics of Cardiometabolic and Renal Traits in African AmericansR01HL133870 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROBERT E GERSZTEN · 2017 to 2026
$6.7M
The Role of SECTM1 in Monocyte Biology and AtherosclerosisK08HL161445 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Usman A. Tahir · 2022 to 2026
$822k
NHLBI NIH HHS K08 HL161445NHLBI NIH HHS R01 HL133870NICHD NIH HHS R01 HD041702NIDDK NIH HHS R01 DK081572
6 · The paper itself

Abstract

Cardiometabolic diseases, including cardiovascular disease and diabetes, are major causes of morbidity and mortality worldwide. Despite progress in prevention and treatment, recent trends show a stalling in the reduction of cardiovascular disease morbidity and mortality, paralleled by increasing rates of cardiometabolic disease risk factors in young adults, underscoring the importance of risk assessments in this population. This review highlights the evidence for molecular biomarkers for early risk assessment in young individuals. We examine the utility of traditional biomarkers in young individuals and discuss novel, nontraditional biomarkers specific to pathways contributing to early cardiometabolic disease risk. Additionally, we explore emerging omic technologies and analytical approaches that could enhance risk assessment for cardiometabolic disease.

Indexed as

Cardiovascular DiseasesBiomarkersHumansRisk AssessmentRisk FactorsYoung AdultBiomarkersbiomarkerscardiovascular diseasedeathmorbiditymortalityyoung adult

Identifiers

PMID37289904
PMCPMC10320574
OpenAlexW4379793763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.