ArticleEmergency radiology2023
High-pitched tin-filtered CT pulmonary angiography in radiation dose reduction for pulmonary embolism investigations in young females.
Article in Emergency radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 7 citations in OpenAlex.
- Dual-energy CT pulmonary angiography using dual-flow mixture bolus tracking: potential for contrast medium and radiation exposure reduction.Insights into imaging · 2026Article
- Performance of iodine quantification through high-pitch dual-source photon-counting CT: a phantom study.Japanese journal of radiology · 2025Article
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Authors and funding
5 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionComputed tomography pulmonary angiography (CTPA) is the gold standard test to investigate pulmonary embolism (PE). This technique carries significant radiation risk in young females because of radiosensitive breast and thyroid tissues. A high-pitched CT technique offers significant radiation dose reduction (RDR) and minimises breathing artefact. The addition of CT tube tin-filtration may offer further RDR. The aim of this retrospective study was to assess RDR and image quality (IQ) of high-pitch tin-filtered (HPTF)-CTPA against conventional-CTPA.
methodsRetrospective review of consecutive adult females age < 50 years undergoing high pitch tin filtration (HPTF) and standard pitch no tin filtration (SPNF) during a 3-year period beginning in November 2017. CTs in both groups were compared for radiation dose, pulmonary arteries contrast density (Hounsfield units (HU)) and movement artefact. Findings of both groups were compared with the Student's T-test and Mann-Whitney U test, where p < 0.05 being considered significant. Diagnostic quality was also recorded.
resultsTen female patients (mean age 33, 6/10 pregnant) in HPTF group and 10 female patients (mean age 36, 1/10 pregnant) in SPNF group were included. The HPTF group achieved 93% RDR (dose length product: 25.15 mGy.cm vs 337.10 mGy.cm, p < 0.01). There was significant contrast density difference between the two groups in the main, left or right pulmonary arteries (322.72 HU, 311.85 HU and 319.41 HU in HPTF group vs 418.60 HU, 405.10 HU and 415.96 HU in SPNF group respectively, p = 0.03, p = 0.03 and p = 0.04). 8/10 HPTF group and 10/10 in the control group were > 250 HU in all three vessels; the remaining 2 HPTF CTPA were > 210HU. All CT scans in both groups were of diagnostic quality and none exhibited movement artefact.
conclusionThis study was the first to demonstrate significant RDR with the HPTF technique whilst maintaining IQ in patients undergoing chest CTPA. This technique is particularly beneficial in young females and pregnant females with suspected PE.
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