Evidence map›Paper›PMID 37289177›Full record

ArticleACS biomaterials science & engineering2023

Biomimetic Electrospun Scaffold-Based In Vitro Model Resembling the Hallmarks of Human Myocardial Fibrotic Tissue.

Gerardina Ruocco, Alice Zoso, Leonardo Mortati, Irene Carmagnola, Valeria Chiono

Open access · hybridAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. A practical toolbox for modelling fibrosis in vitro.Nature biomedical engineering · 2026
    Review
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  3. Article
  4. Article
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  6. Article
  7. Dressed in Collagen: 2D and 3D Cardiac Fibrosis Models.International journal of molecular sciences · 2025
    Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gerardina RuoccoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino TO, Italy.ORCID 0000-0002-9302-5682
Alice ZosoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino TO, Italy.ORCID 0000-0002-1840-8886
Leonardo MortatiIstituto Nazionale di Ricerca Metrologica (INRIM), 10135 Torino TO, Italy.
Irene CarmagnolaDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino TO, Italy.
Valeria ChionoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino TO, Italy.ORCID 0000-0003-2067-7732
Politecnico di Torino · ITIstituto Nazionale di Ricerca Metrologica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse remodeling post-myocardial infarction is hallmarked by the phenotypic change of cardiac fibroblasts (CFs) into myofibroblasts (MyoFs) and over-deposition of the fibrotic extracellular matrix (ECM) mainly composed by fibronectin and collagens, with the loss of tissue anisotropy and tissue stiffening. Reversing cardiac fibrosis represents a key challenge in cardiac regenerative medicine. Reliable

Indexed as

Tissue EngineeringTissue ScaffoldsAnimalsBiomimeticsFibronectinsFibrosisHumansFibronectinscardiac fibrosiselectrospun scaffoldextracellular matrix proteinsin vitro modelsurface modification

Identifiers

PMID37289177
PMCPMC10336747
OpenAlexW4379768343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.