Evidence map›Paper›PMID 37289078›Full record

ArticleJournal of bacteriology2023

Hyperphosphorylation of the Group A Streptococcal Control of Virulence Regulator Increases Promoter Occupancy Specifically at Virulence Factor-Encoding Genes.

Nicola Horstmann, Chau Nguyen Tran, Anthony R Flores, Samuel A Shelburne

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nicola HorstmannDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Chau Nguyen TranDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Anthony R FloresDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School at UTHealth Houston, Houston, Texas, USA.ORCID 0000-0002-6402-4269
Samuel A ShelburneDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-9721-263X
The University of Texas MD Anderson Cancer Center · USThe University of Texas Health Science Center at Houston · US

Funding

Contribution of catabolite control protein A to group A streptococcal virulenceR01AI089891 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHELBURNE, SAMUEL A · 2011 to 2015
$1.6M
NIAID NIH HHS R01 AI089891
6 · The paper itself

Abstract

The

Indexed as

Streptococcal InfectionsVirulence FactorsBacterial ProteinsGene Expression Regulation, BacterialHistidine KinaseHumansPhosphoric Monoester HydrolasesStreptococcus pyogenesVirulenceBacterial ProteinsHistidine KinasePhosphoric Monoester HydrolasesVirulence FactorsChIP-seqCovRSDNA bindingStreptococcus pyogenestwo-component regulatory systems

Identifiers

PMID37289078
PMCPMC10294628
OpenAlexW4379768655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.