Evidence map›Paper›PMID 37288966›Full record

ArticleJournal of veterinary internal medicine

Clinical features, comparative imaging findings, treatment, and outcome in dogs with discospondylitis: A multi-institutional retrospective study.

Cassie Van Hoof, Nicole A Davis, Sheila Carrera-Justiz, Alisha D Kahn, Steven De Decker, Nicholas J Grapes, Michaela Beasley, John Du, Theresa E Pancotto, Anna Suñol and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  5. DisseminatedMedical mycology case reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Cassie Van HoofDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
Nicole A DavisDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
Sheila Carrera-JustizDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.ORCID https://orcid.org/0000-0002-6345-5921
Alisha D KahnDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Steven De DeckerDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, UK.ORCID https://orcid.org/0000-0002-2505-2152
Nicholas J GrapesDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, UK.ORCID https://orcid.org/0000-0002-8849-5508
Michaela BeasleyDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, Mississippi, USA.
John DuDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, Mississippi, USA.
Theresa E PancottoDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Anna SuñolAniCura Ars Veterinaria Hospital, Barcelona, Spain.ORCID https://orcid.org/0000-0003-0985-6959
Richard ShinnDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, USA.ORCID https://orcid.org/0000-0003-4308-4374
Barry DeCiccoCenter for Statistical Training and Consulting (CSTAT), Michigan State University, East Lansing, Michigan, USA.
Erica BurklandACCESS Specialty Animal Hospitals-South Bay, Torrance, California, USA.
Harry CridgeDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.ORCID https://orcid.org/0000-0003-0236-2307
Michigan State University · USMississippi State University · USUniversity of Florida · USUniversity of London · GBAuburn University · USCalifornia Animal Hospital · USVeterinarians Without Borders · USVirginia–Maryland College of Veterinary Medicine · US

Funding

Short-term biomedical research training program for veterinary studentsT35OD016477 · OD · MICHIGAN STATE UNIVERSITY · PI COLLEEN Cosgrove HEGG, Andrea Noel Johnston · 2013 to 2026
$1.5M
NIH HHS T35 OD016477NIH Summer Research Grant Program NIH-5T35OD016477-20
6 · The paper itself

Abstract

backgroundLimited recent data exists regarding discospondylitis in dogs. HYPOTHESIS/

objectives(i) Describe the signalment, clinical and imaging findings, etiologic agents, treatment, and outcome of dogs with discospondylitis, (ii) determine diagnostic agreement between radiographs, CT, and MRI with regard to the presence of discospondylitis and its location, and (iii) determine risk factors for relapse and progressive neurological deterioration. ANIMALS: Three hundred eighty-six dogs.

methodsMulti-institutional retrospective study. Data extracted from medical records were: signalment, clinical and examination findings, diagnostic results, treatments, complications, and outcome. Potential risk factors were recorded. Breed distribution was compared to a control group. Agreement between imaging modalities was assessed via Cohen's kappa statistic. Other analyses were performed on categorical data, using cross tabulations with chi-squared and Fisher's exact tests.

resultsMale dogs were overrepresented (236/386 dogs). L7-S1 (97/386 dogs) was the most common site. Staphylococcus species (23/38 positive blood cultures) were prevalent. There was a fair agreement (κ = 0.22) between radiographs and CT, but a poor agreement (κ = 0.05) between radiographs and MRI with regard to evidence of discospondylitis. There was good agreement between imaging modalities regarding location of disease. Trauma was associated with an increased risk of relapse (P = .01, OR: 9.0, 95% CI: 2.2-37.0). Prior steroid therapy was associated with an increased risk of progressive neurological dysfunction (P = .04, OR: 4.7, 95% CI: 1.2-18.6). CONCLUSIONS AND CLINICAL IMPORTANCE: Radiograph and MRI results could be discrepant in dogs with discospondylitis. Prior trauma and corticosteroids could be associated with relapse and progressive neurological dysfunction, respectively.

Indexed as

DiscitisDog DiseasesAnimalsDogsMagnetic Resonance ImagingMaleRadiographyRecurrenceRetrospective Studiescomputed tomographydiscinfectionradiologyvertebral

Identifiers

PMID37288966
PMCPMC10365064
OpenAlexW4379769311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.