ArticleMicrosystems & nanoengineering2023
Evolution of focused streams for viscoelastic flow in spiral microchannels.
Article in Microsystems & nanoengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- An inertial-based spiral device for separating rare tumor cells from liquid biopsies.Bioengineering & translational medicine · 2026Article
- Fusion dynamics of viscoelastic droplets: Similarities and differences with shape recovery.Biophysical journal · 2026Article
- Article
- High-throughput sheathless focusing and sorting of flexible microalgae in spiral-coupled contraction-expansion channels.Microsystems & nanoengineering · 2025Article
- Computational methods for inertial microfluidics: recent advances and future perspectives.Microsystems & nanoengineering · 2025Review
- Isolation Techniques of Micro/Nano-Scaled Species for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Elasto-inertial focusing and particle migration in high aspect ratio microchannels for high-throughput separation.Microsystems & nanoengineering · 2024Article
- A Novel Electrokinetic-Based Technique for the Isolation of Circulating Tumor Cells.Micromachines · 2023Article
- Sheathless inertial particle focusing methods within microfluidic devices: a review.Frontiers in bioengineering and biotechnology · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Particle migration dynamics in viscoelastic fluids in spiral channels have attracted interest in recent years due to potential applications in the 3D focusing and label-free sorting of particles and cells. Despite a number of recent studies, the underlying mechanism of Dean-coupled elasto-inertial migration in spiral microchannels is not fully understood. In this work, for the first time, we experimentally demonstrate the evolution of particle focusing behavior along a channel downstream length at a high blockage ratio. We found that flow rate, device curvature, and medium viscosity play important roles in particle lateral migration. Our results illustrate the full focusing pattern along the downstream channel length, with side-view imaging yielding observations on the vertical migration of focused streams. Ultimately, we anticipate that these results will offer a useful guide for elasto-inertial microfluidics device design to improve the efficiency of 3D focusing in cell sorting and cytometry applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.