Evidence map›Paper›PMID 37288313›Full record

ArticleBrain communications2023

Genome-phenome wide association study of broadly defined headache.

Wan-Ting Hsu, Yu-Ting Lee, Jasmine Tan, Yung-Han Chang, Frank Qian, Kuei-Yu Liu, Jo-Ching Hsiung, Chia-Hung Yo, Sung-Chun Tang, Xia Jiang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Wan-Ting HsuDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Yu-Ting LeeHealth Data Science Research Group, National Taiwan University Hospital, Taipei 100, Taiwan.
Jasmine TanHealth Data Science Research Group, National Taiwan University Hospital, Taipei 100, Taiwan.
Yung-Han ChangDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.
Frank QianDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Kuei-Yu LiuHealth Data Science Research Group, National Taiwan University Hospital, Taipei 100, Taiwan.
Jo-Ching HsiungDepartment of Pediatrics, Einstein Medical Center-Philadelphia, National Taiwan University Hospital, Philadelphia, PA 19141, USA.
Chia-Hung YoDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan.
Sung-Chun TangDepartment of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID https://orcid.org/0000-0003-3731-5973
Xia JiangDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.ORCID https://orcid.org/0000-0001-5878-8986
Chien-Chang LeeHealth Data Science Research Group, National Taiwan University Hospital, Taipei 100, Taiwan.
National Taiwan University Hospital · TWHarvard University · USBeth Israel Deaconess Medical Center · USEinstein Medical Center Philadelphia · USFar Eastern Memorial Hospital · TWUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until recently, most genetic studies of headache have been conducted on participants with European ancestry. We therefore conducted a large-scale genome-wide association study of self-reported headache in individuals of East Asian ancestry (specifically those who were identified as Han Chinese). In this study, 108 855 participants were enrolled, including 12 026 headache cases from the Taiwan Biobank. For broadly defined headache phenotype, we identified a locus on Chromosome 17, with the lead single-nucleotide polymorphism rs8072917 (odds ratio 1.08,

Indexed as

genome-wide association studyheadachemigrainephenome-wide association studyPheWAS

Identifiers

PMID37288313
PMCPMC10243784
OpenAlexW4377965892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.