Evidence map›Paper›PMID 37288097›Full record

ArticleACS catalysis2023

Fully Biocatalytic Rearrangement of Furans to Spirolactones.

Yu-Chang Liu, J D Rolfes, Joel Björklund, Jan Deska

Open access · hybridAbstract read
In one paragraph

Article in ACS catalysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yu-Chang LiuDepartment of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, 00560 Helsinki, Finland.ORCID https://orcid.org/0000-0002-3898-0695
J D RolfesAlbert Hofmann Institute for Physiochemical Sustainability, Albert-Schweitzer-Street 22, 32602 Vlotho, Germany.
Joel BjörklundDepartment of Chemistry, Aalto University, Kemistintie 1, 02150 Espoo, Finland.
Jan DeskaDepartment of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, 00560 Helsinki, Finland.ORCID https://orcid.org/0000-0003-4622-2365
University of Helsinki · FIAalto University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multienzymatic pathway enables the preparation of optically pure spirolactone building blocks. In a streamlined one-pot reaction cascade, the combination of chloroperoxidase, an oxidase, and an alcohol dehydrogenase renders an efficient reaction cascade for the conversion of hydroxy-functionalized furans to the spirocyclic products. The fully biocatalytic method is successfully employed in the total synthesis of the bioactive natural product (+)-crassalactone D, and as the key module in a chemoenzymatic route yielding lanceolactone A.

Identifiers

PMID37288097
PMCPMC10242749
OpenAlexW4376611144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.