Evidence map›Paper›PMID 37287876›Full record

ArticleBiophysics reports2022

Fast cross-linking by DOPA2 promotes the capturing of a stereospecific protein complex over nonspecific encounter complexes.

Jian-Hua Wang, Zhou Gong, Xu Dong, Shu-Qun Liu, Yu-Liang Tang, Xiaoguang Lei, Chun Tang, Meng-Qiu Dong

Open access · diamondAbstract read
In one paragraph

Article in Biophysics reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jian-Hua WangNational Institute of Biological Sciences (NIBS), Beijing 102206, China.
Zhou GongState Key Laboratory of Magnetic Resonance and Atomic Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China.
Xu DongState Key Laboratory of Magnetic Resonance and Atomic Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China.
Shu-Qun LiuState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming 650091, China.
Yu-Liang TangBeijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Center for Quantitative Biology, Peking-Tsinghua Center for Life Science, Peking University, Beijing 100871, China.
Xiaoguang LeiBeijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Center for Quantitative Biology, Peking-Tsinghua Center for Life Science, Peking University, Beijing 100871, China.
Chun TangBeijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Center for Quantitative Biology, Peking-Tsinghua Center for Life Science, Peking University, Beijing 100871, China.
Meng-Qiu DongNational Institute of Biological Sciences (NIBS), Beijing 102206, China.
Center for Life Sciences · CNChinese Academy of Sciences · CNNational Institute of Biological Sciences, Beijing · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient and weak protein-protein interactions are essential to many biochemical reactions, yet are technically challenging to study. Chemical cross-linking of proteins coupled with mass spectrometry analysis (CXMS) provides a powerful tool in the analysis of such interactions. Central to this technology are chemical cross-linkers. Here, using two transient heterodimeric complexes EIN/HPr and EIIA

Indexed as

Chemical cross-linkingCross-linkerDOPA2DSSEncounter complexesMass spectrometryStereospecific complexTransient protein–protein interaction

Identifiers

PMID37287876
PMCPMC10166511
OpenAlexW4321237739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.