Evidence map›Paper›PMID 37287631›Full record

ReviewFrontiers in pediatrics2023

Between Scylla and Charybdis: thrombosis in children with hemophilia.

Jad El Maamari, Ali Amid, Marie-Claude Pelland-Marcotte, Soumitra Tole

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jad El MaamariDivision of Pediatric Hematology/Oncology, Department of Pediatrics, BC Children's Hospital, Vancouver, BC, Canada.
Ali AmidDivision of Pediatric Hematology/Oncology, Department of Pediatrics, BC Children's Hospital, Vancouver, BC, Canada.
Marie-Claude Pelland-MarcotteDivision of Pediatric Hematology-Oncology, CHU de Québec-Centre Mère-Enfant Soleil, Quebec City, QC, Canada.
Soumitra ToleDepartment of Pediatrics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
British Columbia Children's Hospital · CAHôpital de l'Enfant-Jésus · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thromboembolism is an infrequent complication in children with hemophilia that has been traditionally associated with the presence of a central venous access device. Novel rebalancing agents have shown promising results as prophylactic therapies to minimize the risk of bleeding but both thromboembolism and thrombotic microangiopathy have been reported as complications. The management of thrombosis in children with hemophilia is particularly challenging given the inherent risk of bleeding. In this paper, we present clinical vignettes to review the literature, highlight challenges, and describe our approach to managing thromboembolism in children with hemophilia.

Indexed as

childrenCVADemicizumabhemophiliathrombosis

Identifiers

PMID37287631
PMCPMC10242037
OpenAlexW4378078490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.