Evidence map›Paper›PMID 37287582›Full record

ArticleNeuro-oncology advances2023

The clinical and genomic features of seizures in meningiomas.

Alper Dincer, Muhammad I Jalal, Trisha P Gupte, Shaurey Vetsa, Sagar Vasandani, Kanat Yalcin, Neelan Marianayagam, Nicholas Blondin, Zachary Corbin, Declan McGuone and 4 more

Open access · goldAbstract read
In one paragraph

Article in Neuro-oncology advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Pediatric meningioma and seizures: a single-center cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Pediatric meningioma and seizures: A scoping review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Alper DincerDepartment of Neurosurgery, Tufts Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8078-3214
Muhammad I JalalDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Trisha P GupteDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Shaurey VetsaDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0001-8651-0690
Sagar VasandaniDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Kanat YalcinDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Neelan MarianayagamDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0003-0804-9274
Nicholas BlondinChenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Zachary CorbinChenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-9831-8847
Declan McGuoneChenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Robert K FulbrightChenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-8204-3594
Zeynep Erson-OmayDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0003-1839-5912
Murat GünelDepartment of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0003-3481-2026
Jennifer MoliternoChenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Yale Cancer Center · USTufts Medical Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Meningiomas are the most common central nervous system tumors. Although these tumors are extra-axial, a relatively high proportion (10%-50%) of meningioma patients have seizures that can substantially impact the quality of life. Meningiomas are believed to cause seizures by inducing cortical hyperexcitability that results from mass effect and cortical irritation, brain invasion, or peritumoral brain edema. In general, meningiomas that are associated with seizures have aggressive features, with risk factors including atypical histology, brain invasion, and higher tumor grade. Somatic

Indexed as

meningiomaNF2seizures

Identifiers

PMID37287582
PMCPMC10243847
OpenAlexW4379769113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.