Evidence map›Paper›PMID 37287580›Full record

ArticleNeuro-oncology advances2023

Pediatric meningiomas: A literature review and diagnostic update.

Arnault Tauziède-Espariat, Stefan M Pfister, Christian Mawrin, Felix Sahm

Abstract read
In one paragraph

Article in Neuro-oncology advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. WHO grade 3 pediatric meningioma: a systematic review of clinical features and patient-level analysis of prognostic factors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Pooled it
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  5. [Pediatric parasagittal meningioma, case report].Revista medica del Instituto Mexicano del Seguro Social · 2026
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  12. Malignant meningioma of the falx cerebri in a child: case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arnault Tauziède-EspariatDepartment of Neuropathology, Sainte-Anne Hospital, Paris, France.
Stefan M PfisterHopp Children's Cancer Center (KiTZ) Heidelberg, Heidelberg, Germany.
Christian MawrinDepartment of Neuropathology, Otto-von-Guericke University Hospital, Magdeburg, Germany.
Felix SahmHopp Children's Cancer Center (KiTZ) Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0001-5441-1962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Meningiomas have always represented the most frequently observed primary central nervous system (CNS) tumor in adults. Multiple advances concerning the genetic and epigenetic characterizations of adult meningiomas have been made over the last few years, and a new proposition for integrated histo-molecular grading has recently been offered in the literature. Pediatric meningiomas represent a very small proportion of all diagnosed meningiomas. New literature has determined that pediatric meningiomas are clinically, histopathologically, genetically, and epigenetically distinct from their adult counterparts. Herein, we reviewed and performed a synthesis of literature investigating pediatric meningiomas. We then compared and contrasted pediatric meningiomas with their adult counterparts. Methods: We performed an extensive review of cases from English-language literature available in Pubmed using the keywords "pediatric" and "meningioma" as well as "children" and "meningioma". We reviewed and analyzed fifty-six papers that include 498 cases. Results: This literature review revealed that pediatric meningiomas differ from their adult counterparts clinically (location, sex ratio) and also in terms of etiology (germline mutations), histopathology (a greater incidence of clear cell subtype), molecular biology, and epigenetics. Conclusions: Pediatric meningiomas are, like other brain tumors (such as low-grade and high-grade gliomas), clinically and biologically different from their adult counterparts. Further studies are needed to better understand the tumorigenesis of pediatric meningiomas and to optimize their stratification in terms of outcome and therapeutic strategy.

Indexed as

meningiomapediatric

Identifiers

PMID37287580
PMCPMC10243870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.