Evidence map›Paper›PMID 37287523›Full record

ArticleObesity science & practice2023

Interaction between increasing body mass index and spinal cord injury to the probability of developing a diagnosis of nonalcoholic fatty liver disease.

Dan Eisenberg, Katherine D Arnow, Nicolas B Barreto, Kristen Davis, Sherri L LaVela, Susan M Frayne, Andrea L Nevedal, Justina Wu, Alex H S Harris

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dan EisenbergCenter for Innovation to Implementation VA Palo Alto Health Care System Palo Alto California USA.ORCID https://orcid.org/0000-0002-5908-3942
Katherine D ArnowStanford-Surgery Policy Improvement Research & Education Center Stanford School of Medicine Stanford California USA.
Nicolas B BarretoStanford-Surgery Policy Improvement Research & Education Center Stanford School of Medicine Stanford California USA.
Kristen DavisStanford-Surgery Policy Improvement Research & Education Center Stanford School of Medicine Stanford California USA.
Sherri L LaVelaCenter of Innovation for Complex Chronic Care VA Edward Hines Jr Hines Illinois USA.
Susan M FrayneCenter for Innovation to Implementation VA Palo Alto Health Care System Palo Alto California USA.
Andrea L NevedalCenter for Innovation to Implementation VA Palo Alto Health Care System Palo Alto California USA.
Justina WuCenter for Innovation to Implementation VA Palo Alto Health Care System Palo Alto California USA.
Alex H S HarrisCenter for Innovation to Implementation VA Palo Alto Health Care System Palo Alto California USA.
VA Palo Alto Health Care System · USStanford Medicine · USNorthwestern University · US

Funding

Body Mass Index (BMI) Risk Zones and Variations in Obesity Detection in Veterans with Spinal Cord Injury (SCI)I01HX002432 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI EISENBERG, DAN · 2020 to 2022
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HSRD VA I01 HX002432
6 · The paper itself

Abstract

Background: The prevalence of obesity and comorbidities is high in the population with spinal cord injury (SCI). We sought to determine the effect of SCI on the functional form of the relationship between body mass index (BMI) and risk of developing nonalcoholic fatty liver disease (NAFLD), and assess whether SCI-specific mapping of BMI to risk of developing NAFLD is needed. Methods: Longitudinal cohort study comparing Veterans Health Administration patients with a diagnosis of SCI to a 1:2 matched control group without SCI. The relationship between BMI and development of NAFLD at any time was assessed with propensity score matched Cox regression models; NAFLD development at 10-year with a propensity score matched logistic model. The positive predictive value of developing NAFLD at 10 years was calculated for BMI 19-45 kg/m Results: 14,890 individuals with SCI met study inclusion criteria, and 29,780 Non-SCI individuals in matched control group. Overall, 9.2% in SCI group and 7.3% in Non-SCI group developed NAFLD during the study period. A logistic model assessing the relationship between BMI and the probability of developing a diagnosis of NAFLD demonstrated that the probability of developing disease increased as BMI increased in both cohorts. The probability was significantly higher in the SCI cohort at each BMI threshold ( Conclusions: The probability of developing NAFLD is greater in individuals with SCI than without SCI, at every BMI level 19 kg/m

Indexed as

body mass indexnonalcoholic fatty liver diseaseobesityspinal cord injuryveterans

Identifiers

PMID37287523
PMCPMC10242254
OpenAlexW4300817626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.