Evidence map›Paper›PMID 37287522›Full record

ArticleObesity science & practice2023

Dietary advanced glycation products and their associations with insulin sensitivity and body weight: A 16-week randomized clinical trial.

Hana Kahleova, Tatiana Znayenko-Miller, Jaime Uribarri, Richard Holubkov, Neal D Barnard

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02939638 (A Randomized, Controlled Trial on Diet, Insulin Sensitivity, and Postprandial Metabolism), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02939638 nacompletednot on this map

A Randomized, Controlled Trial on Diet, Insulin Sensitivity, and Postprandial Metabolism

TypeinterventionalSponsorPhysicians Committee for Responsible MedicineRan2016 to 2019Enrolled220ConditionsOverweight, Obesity, Insulin ResistanceArmsPlant-based diet, Control Diet
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Dietary Advanced Glycation End Products and Cardiovascular-Kidney-Metabolic Complications.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  2. Not all ultra-processed foods are created equal: a review.BMJ nutrition, prevention & health · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hana KahleovaPhysicians Committee for Responsible Medicine Washington District of Columbia USA.ORCID https://orcid.org/0000-0003-0491-3993
Tatiana Znayenko-MillerPhysicians Committee for Responsible Medicine Washington District of Columbia USA.
Jaime UribarriIcahn School of Medicine at Mount Sinai New York New York USA.
Richard HolubkovSchool of Medicine University of Utah Salt Lake Utah USA.
Neal D BarnardPhysicians Committee for Responsible Medicine Washington District of Columbia USA.
Physicians Committee for Responsible Medicine · USIcahn School of Medicine at Mount Sinai · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Evidence suggests that changes in advanced glycation end-products (AGEs) may influence body weight. Previous studies have focused on cooking methods as the primary way how to reduce the dietary AGEs but little is known about the effects of a change in diet composition. Objective: The aim of this study was to assess the effects of a low-fat plant-based diet on dietary AGEs and test the association with body weight, body composition, and insulin sensitivity. Methods: Participants who were overweight ( Results: Dietary AGEs decreased in the intervention group by 8768 ku/day on average (95% -9611 to -7925; Conclusions: Dietary AGEs decreased on a low-fat plant-based diet, and this decrease was associated with changes in body weight, body composition, and insulin sensitivity, independent of energy intake. These findings demonstrate positive effects of qualitative dietary changes on dietary AGEs and cardiometabolic outcomes. Clinical Trial Registry Number: NCT02939638.

Indexed as

advanced glycation end‐productsdietnutritionveganweight

Identifiers

PMID37287522
PMCPMC10242260
OpenAlexW4306398937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.