Evidence map›Paper›PMID 37287466›Full record

ArticleFrontiers in cellular and infection microbiology2023

Variation in CD8 T cell IFNγ differentiation to strains of

Angel K Kongsomboonvech, Laura García-López, Ferdinand Njume, Felipe Rodriguez, Scott P Souza, Alex Rosenberg, Kirk D C Jensen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Susceptibility ofmBio · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Angel K KongsomboonvechDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
Laura García-LópezDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
Ferdinand NjumeDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
Felipe RodriguezDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
Scott P SouzaDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
Alex RosenbergThe Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Kirk D C JensenDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
University of California, Merced · USUniversity of Georgia · US

Funding

New requirements for immunity to parasitic pathogens - when vaccines work and why they failR01AI137126 · NIAID · UNIVERSITY OF CALIFORNIA, MERCED · PI JENSEN, KIRK DAVID CHRISTIAN · 2018 to 2022
$2.0M
Masters of immunology- how Toxoplasma gondii directly manipulates T cell activationR15AI131027 · NIAID · UNIVERSITY OF CALIFORNIA, MERCED · PI JENSEN, KIRK DAVID CHRISTIAN · 2018 to 2019
$525k
NIAID NIH HHS R01 AI137126NIAID NIH HHS R15 AI131027
6 · The paper itself

Abstract

Introduction: Methods: Therefore, we screened F1 progeny from genetic crosses between the clonal lineage strains to identify ROCTR. Naïve antigen-specific CD8 T cells (T57) isolated from transnuclear mice, which are specific for the endogenous and vacuolar TGD057 antigen, were measured for their ability to become activated, transcribe Results: Genetic mapping returned four non-interacting quantitative trait loci (QTL) with small effect on Discussion: Collectively, our data suggest that while CD8 T cell IFNγ production to

Indexed as

ToxoplasmaAnimalsCD8-Positive T-LymphocytesCell DifferentiationInterferon-gammaMiceProtozoan ProteinsQuantitative Trait LociInterferon-gammaProtozoan ProteinsCD8 T cellGRA43IFN-gammaQTL (quantitative trait loci)RIPK3ROP16TgNSMToxoplasm gondii

Identifiers

PMID37287466
PMCPMC10242045
OpenAlexW4377823053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.