Evidence map›Paper›PMID 37287319›Full record

ArticleJournal of the National Cancer Institute2023

Urgent need to mitigate disparities in federal funding for cancer research.

Shida Haghighat, Chunsu Jiang, Wael El-Rifai, Alexander Zaika, David S Goldberg, Shria Kumar

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
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  9. Article
  10. Article
  11. Addressing disparities in funding for robust cancer research.Therapeutic advances in vaccines and immunotherapy · 2023
    Article
  12. Article
  13. Cancer statistics, 2025.CA: a cancer journal for clinicians
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shida HaghighatDivision of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-1416-3930
Chunsu JiangDivision of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, Miami, FL, USA.
Wael El-RifaiSylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL, USA.
Alexander ZaikaSylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL, USA.
David S GoldbergDivision of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, Miami, FL, USA.
Shria KumarDivision of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

SOX4-Mediated Transcription Program in Esophageal AdenocarcinomaP01CA268991 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI WAEL EL-RIFAI · 2022 to 2026
$9.2M
Regulation of the Oncogenic Stress Response in Helicobacter pylori-infected cellsR01CA138833 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALEXANDER I. ZAIKA · 2010 to 2026
$4.3M
Mechanisms of Tumorigenic Transformation of Barretts EsophagusR01CA206564 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZAIKA, ALEXANDER I. · 2015 to 2019
$1.8M
Translational Research Training in Gastroenterology and HepatologyT32DK116678 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ABREU, MARIA TERESA · 2018 to 2022
$678k
BLRD Research Career Scientist Award ApplicationIK6BX003787 · VA · VETERANS HEALTH ADMINISTRATION · PI WAEL EL-RIFAI · 2017 to 2026
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BLRD Research Career Scientist Award ApplicationIK6BX006300 · VA · MIAMI VA HEALTH CARE SYSTEM · PI ZAIKA, ALEXANDER I. · 2023 to 2025
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Regulation of gastroesophageal reflux-associated tumorigenesisI01BX002115 · VA · VETERANS HEALTH ADMINISTRATION · PI ZAIKA, ALEXANDER I. · 2014 to 2024
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BLRD VA I01 BX002115BLRD VA IK6 BX003787BLRD VA IK6 BX006300NCI NIH HHS P01 CA268991NCI NIH HHS R01 CA138833NCI NIH HHS R01 CA206564NIDDK NIH HHS T32 DK116678
6 · The paper itself

Abstract

We evaluate National Cancer Institute (NCI) funding distribution to the most common cancers, considering their respective public health burdens, and explore associations between funding and racial and ethnic burden of disease. The NCI's Surveillance, Epidemiology and End Results, US Cancer Statistics database, and Funding Statistics were used to calculate funding-to-lethality (FTL) scores. Breast and prostate cancer had the first (179.65) and second (128.90) highest FTL scores, and esophagus and stomach cancer ranked 18th (2.12) and 19th (1.78). We evaluated whether there were differences between the FTL and cancer incidence and/or mortality within individual racial and ethnic groups. NCI funding correlated highly with cancers afflicting a higher proportion of non-Hispanic White individuals (Spearman correlation coefficient = 0.84; P < .001). Correlation was stronger for incidence than mortality. These data reveal that funding across cancer sites is not concordant with lethality and that cancers with high incidence among racial and ethnic minorities receive lower funding.

Indexed as

NeoplasmsEthnicityHumansMaleRacial GroupsUnited StatesWhite

Identifiers

PMID37287319
PMCPMC10560596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.