Evidence map›Paper›PMID 37287038›Full record

ArticleWorld journal of surgical oncology2023

Use of sentinel lymph node biopsy in elderly patients with breast cancer - 10-year experience from a Swiss university hospital.

Martin Heidinger, Nadia Maggi, Gilles Dutilh, Madleina Mueller, Ruth S Eller, Julie M Loesch, Fabienne D Schwab, Christian Kurzeder, Walter P Weber

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Martin Heidinger *Breast Center, University Hospital Basel, Basel, Switzerland. martin.heidinger@usb.ch.ORCID http://orcid.org/0000-0003-2816-1351
Nadia Maggi *Breast Center, University Hospital Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-9483-0245
Gilles DutilhDepartment of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-6719-2508
Madleina MuellerBreast Center, University Hospital Basel, Basel, Switzerland.
Ruth S EllerBreast Center, University Hospital Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0003-0573-4452
Julie M LoeschBreast Center, University Hospital Basel, Basel, Switzerland.
Fabienne D SchwabBreast Center, University Hospital Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0003-1124-3780
Christian KurzederBreast Center, University Hospital Basel, Basel, Switzerland.
Walter P WeberBreast Center, University Hospital Basel, Basel, Switzerland.
University of Basel · CHBreast Center · CHUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Choosing Wisely initiative recommended the omission of routine sentinel lymph node biopsy (SLNB) in patients ≥ 70 years of age, with clinically node-negative, early stage, hormone receptor (HR) positive and human epidermal growth factor receptor 2 (Her2) negative breast cancer in August 2016. Here, we assess the adherence to this recommendation in a Swiss university hospital.

methodsWe conducted a retrospective single center cohort study from a prospectively maintained database. Patients ≥ 18 years of age with node-negative breast cancer were treated between 05/2011 and 03/2022. The primary outcome was the percentage of patients in the Choosing Wisely target group who underwent SLNB before and after the initiative went live. Statistical significance was tested using chi-squared test for categorical and Wilcoxon rank-sum tests for continuous variables.

resultsIn total, 586 patients met the inclusion criteria with a median follow-up of 2.7 years. Of these, 163 were ≥ 70 years of age and 79 were eligible for treatment according to the Choosing Wisely recommendations. There was a trend toward a higher rate of SLNB (92.7% vs. 75.0%, p = 0.07) after the Choosing Wisely recommendations were published. In patients ≥ 70 years with invasive disease, fewer received adjuvant radiotherapy after omission of SLNB (6.2% vs. 64.0%, p < 0.001), without differences concerning adjuvant systemic therapy. Both short-term and long-term complication rates after SLNB were low, without differences between elderly patients and those < 70 years.

conclusionsChoosing Wisely recommendations did not result in a decreased use of SLNB in the elderly at a Swiss university hospital.

Indexed as

Breast NeoplasmsSentinel Lymph NodeAgedAxillaCohort StudiesFemaleHospitalsHumansLymph Node ExcisionLymph NodesRetrospective StudiesSentinel Lymph Node BiopsySwitzerlandAxillary stagingAxillary surgeryBreast cancerBreast cancer surgeryElderlySentinel lymph node biopsy

Identifiers

PMID37287038
PMCPMC10249276
OpenAlexW4379741685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.