Evidence map›Paper›PMID 37287001›Full record

ReviewChinese medicine2023

Technical guidelines for risk assessment of heavy metals in traditional Chinese medicines.

Tian-Tian Zuo, Lei Zhang, Ying Wang, Li-Xing Nie, Ming-Rui Shen, Li-Na Liu, Jian-Dong Yu, Hong-Yu Jin, Feng Wei, Shuang-Cheng Ma

Open access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tian-Tian ZuoNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China.
Lei ZhangChina National Center for Food Safety Risk Assessment, Beijing, 100082, China.
Ying WangNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China.
Li-Xing NieNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China.
Ming-Rui ShenChinese Pharmacopeia Commission, Beijing, 100061, China.
Li-Na LiuNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China.
Jian-Dong YuNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China.
Hong-Yu JinNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China. jhyu@nifdc.org.cn.
Feng WeiNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China. weifeng@nifdc.org.cn.
Shuang-Cheng MaNational Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing, 102629, China. masc@nifdc.org.cn.
National Institutes for Food and Drug Control · CNChina National Health Development Research Center · CNChina National Center for Food Safety Risk Assessment · CN

Funding

13th 5 Year National Significant New Drugs Creation Feature Subjects 2018ZX09735006Youth Development Research Foundation of NIFDC 2020A3
6 · The paper itself

Abstract

backgroundHeavy metals are considered a global concern because they can deteriorate human health. This guideline aims to scientifically evaluate health risk of heavy metals in TCM and to propose a reference for decision making in developing TCM-related health policies.

methodsUsing a multidisciplinary approach, a steering committee oversaw the development of the guideline. To obtain a reasonable and accurate risk assessment, key exposure assessment parameters for TCM, e.g., exposure frequency (EF), exposure duration (ED), and daily ingestion rate (IR) were obtained from surveys. In addition, transfer rates for heavy metals from Chinese medicinal materials (CMM) to decoctions or preparations were examined.

resultsBased on the scientific theory of risk control, the guideline was designed systematically, and principles and procedures for the risk assessment of heavy metals in TCM were identified. The guideline can be utilized to assess the risk of heavy metals in CMM and Chinese patent medicines (CPM).

conclusionThis guideline may help standardize the risk assessment of heavy metals in TCM, advance regulatory standards for heavy metals in TCM, and ultimately improve human health through scientific TCM usage in clinic.

Indexed as

GuidelineHeavy metalsRisk assessmentTraditional Chinese medicine

Identifiers

PMID37287001
PMCPMC10245643
OpenAlexW4379768112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.