ArticleBMC ophthalmology2023
Evaluation of Schlemm's canal with swept-source optical coherence tomography in primary angle-closure disease.
Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Anterior segment optical coherence tomography assessment of Schlemm's canal before and after Descemet membrane endothelial keratoplasty: A retrospective observational study.Indian journal of ophthalmology · 2026Observational
- Impact of Ocular Massage on Intraocular Pressure and Schlemm Canal Dimensions in Healthy Adults: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- The impact of graves' orbitopathy on anterior segment structures and choroidal parameters.BMC ophthalmology · 2025Article
- Real world outcomes of Kahook Dual Blade goniotomy in black and Afro-Latinx adult patients with glaucoma: a 2-year retrospective study.Frontiers in ophthalmology · 2025Article
- Assessment of Schlemm's canal with swept-source optical coherence tomography in Graves' ophthalmopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Observational
- Correction: Evaluation of Schlemm's canal with swept-source optical coherence tomography in primary angle-closure disease.BMC ophthalmology · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
purposeTo perform an in vivo evaluation of the changes in Schlemm's canal (SC) among patients with primary angle-closure disease (PACD) using swept-source optical coherence tomography (SS-OCT).
methodsPatients diagnosed with PACD who had not undergone surgery were recruited. The SS-OCT quadrants scanned herein included the nasal and temporal sections at 3 and 9 o'clock, respectively. The diameter and cross-sectional area of the SC were measured. A linear mixed-effects model was performed to analyze the effects of parameters on the SC changes. The hypothesis of interest was related to the angle status (iridotrabecular contact, ITC/open angle, OPN), which was further explored with pairwise comparisons of the estimated marginal means (EMMs) of the SC diameter and SC area. In the ITC regions, the relationship between the trabecular-iris contact length (TICL) percentage and SC parameters was also studied by a mixed model.
resultsA total of 49 eyes of 35 patients were included for measurements and analysis. The percentage of observable SCs in the ITC regions was only 58.5% (24/41), whereas it was 86.0% (49/57) in the OPN regions (χ
conclusionsThe morphologies of SC could be affected by the angle status (ITC/OPN) in patients with PACD, and ITC was significantly associated with a decreasing SC size. These changes in SC as described by OCT scans might help to elucidate the progression mechanisms of PACD.
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