Evidence map›Paper›PMID 37286755›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2023

N6-methyladenosine (m6A) Modification in Preeclampsia.

Tingting Zhang, Ziyan Jiang, Nana Yang, Zhiping Ge, Qing Zuo, Shiyun Huang, Lizhou Sun

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tingting ZhangDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China.ORCID 0000-0002-7865-3613
Ziyan JiangDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China.
Nana YangDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China.
Zhiping GeDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China.
Qing ZuoDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China.
Shiyun HuangDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China.
Lizhou SunDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province, Nanjing, 210029, People's Republic of China. sunlizhou@njmu.edu.cn.
Jiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, epitranscriptional modification of N6-methyladenosine (m6A) has received growing attention in the research on the pathogenesis of preeclampsia. Advances in m6A sequencing have revealed the molecular mechanism and importance of m6A modification. In addition, epitranscriptional modification of m6A is closely related to the metabolic processes of placental tissues and cells in preeclampsia. This article reviews the composition, mode of action, and bioinformatics analysis of m6A modification-related proteins, and their biological function in the progression of preeclampsia. The relationship between m6A modification and preeclampsia risk factors, such as diabetes, cardiovascular disease, obesity, and psychological stress, is summarized to provide new ideas for studying PE-targeting molecules.

Indexed as

Cardiovascular DiseasesPre-EclampsiaAdenosineFemaleHumansPlacentaPregnancyAdenosineN6-methyladenosinePlacentaPreeclampsiaTrophoblast

Identifiers

PMID37286755
OpenAlexW4379623051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.