Evidence map›Paper›PMID 37286567›Full record

ArticleNPJ microgravity2023

Myeloid cell infiltration in skeletal muscle after combined hindlimb unloading and radiation exposure in mice.

Eric B Emanuelsson, Bjorn Baselet, Mieke Neefs, Sarah Baatout, Brit Proesmans, Lisa Daenen, Carl Johan Sundberg, Helene Rundqvist, Rodrigo Fernandez-Gonzalo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ microgravity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eric B EmanuelssonDepartment of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-2746-8581
Bjorn BaseletRadiobiology unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.ORCID http://orcid.org/0000-0001-9840-2822
Mieke NeefsRadiobiology unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.
Sarah BaatoutRadiobiology unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.ORCID http://orcid.org/0000-0001-8110-751X
Brit ProesmansRadiobiology unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.
Lisa DaenenRadiobiology unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.
Carl Johan SundbergDepartment of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Helene RundqvistDepartment of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-5617-9076
Rodrigo Fernandez-GonzaloDepartment of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden. rodrigo.fernandez-gonzalo@ki.se.ORCID http://orcid.org/0000-0003-2816-9855

Funding

Swedish National Space Board (Svenska Rymdstyrelsen) 2021-00159
6 · The paper itself

Abstract

The skeletal muscle and the immune system are heavily affected by the space environment. The crosstalk between these organs, although established, is not fully understood. This study determined the nature of immune cell changes in the murine skeletal muscle following (hindlimb) unloading combined with an acute session of irradiation (HLUR). Our findings show that 14 days of HLUR induces a significant increase of myeloid immune cell infiltration in skeletal muscle.

Identifiers

PMID37286567
PMCPMC10247796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.