Evidence map›Paper›PMID 37286174›Full record

ArticleBrain, behavior, and immunity2023

The future is dynamic: A call for intensive longitudinal data in immunopsychiatry.

Daniel P Moriarity, George M Slavich

Abstract read
In one paragraph

Article in Brain, behavior, and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. From Stress to Synapse: The Neuronal Atrophy Pathway to Mood Dysregulation.International journal of molecular sciences · 2025
    Review
  12. How community connection, homophobia, and racism shape gene expression in sexual minority men with and without HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  13. Observational
  14. Review
  15. Moving toward affective immunology: Legacy and future directions.Comprehensive psychoneuroendocrinology · 2024
    Article
  16. Article
  17. Toward a dynamic immunopsychiatry.Brain, behavior, and immunity · 2024
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel P MoriarityDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA. Electronic address: dmoriarity@mednet.ucla.edu.
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA.

Funding

Testing a Social Safety Theory Perspective on Depression: An Intensive Longitudinal Immunopsychiatric Data ApproachF32MH130149 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MORIARITY, DANIEL P · 2022 to 2024
$210k
NIMH NIH HHS F32 MH130149
6 · The paper itself

Abstract

The long-term value of immunopsychiatry will be based on its ability to translate basic science into effective clinical interventions. In this article, we discuss a key obstacle to achieving this important translational goal-namely, the preponderance of studies that are cross-sectional, or that have months-to-years long follow-up periods. Immunopsychiatric processes such as stress, inflammation, and depression symptoms are inherently dynamic and fluctuate over hours, days, and weeks. This fact suggests that higher-density data collection with only days between measurements is necessary to capture-with adequate resolution-the actual dynamics of these systems, determine optimal time lags with which to observe associations between variables of interest, and maximize the translational potential of these data. To illustrate these points, we use pilot data from our own intensive longitudinal immunopsychiatric study. We then conclude by making several recommendations for future research. By learning how to better use existing data for dynamically informative studies as well as collecting intensive longitudinal data, we believe immunopsychiatry will be much better positioned to advance our causal understanding of the interplay between the immune system and health.

Indexed as

InflammationPsychoneuroimmunologyCross-Sectional StudiesHumansDynamic modelingImmunopsychiatryInflammationIntensive longitudinal designsPsychoneuroimmunologyWithin-person effects

Identifiers

PMID37286174
PMCPMC10411233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.