Evidence map›Paper›PMID 37286131›Full record

ArticleContemporary clinical trials2023

Decision support training for advanced cancer family caregivers: Study protocol for the CASCADE factorial trial.

Shena Gazaway, Rachel D Wells, Andres Azuero, Maria Pisu, Kate Guastaferro, Christine Rini, Richard Taylor, Rhiannon D Reed, Erin R Harrell, Avery C Bechthold and 8 more

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04803604 (Decision Support Training for Advanced Cancer Family Caregivers), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04803604 naactive not recruitingnot on this map

Decision Support Training for Advanced Cancer Family Caregivers: The CASCADE Factorial Trial

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2022 to 2027Enrolled256ConditionsFamily Members, CancerArmsCASCADE (CAre Supporters Coached to be Adept DEcision partners)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Shena GazawaySchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Rachel D WellsSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Andres AzueroSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Maria PisuDivision of Preventive Medicine, UAB Heersink School of Medicine, Birmingham, AL, USA.
Kate GuastaferroDepartment of Social and Behavioral Sciences, School of Global Public Health, New York University, New York, USA.
Christine RiniCancer Survivorship Institute, Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Richard TaylorSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Rhiannon D ReedDivision of Transplantation, Department of Medicine, UAB, Birmingham, AL, USA.
Erin R HarrellDepartment of Psychology, University of Alabama, Tuscaloosa, AL, USA.
Avery C BechtholdSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Reed W BratchesSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Peg McKieSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Jane LowersDivision of Palliative Medicine, Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Grant R WilliamsO'Neal Comprehensive Cancer Center, Birmingham, AL, USA.
Abby R RosenbergDepartment of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Department of Medicine, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Marie A BakitasSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Dio KavalieratosDivision of Palliative Medicine, Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
J Nicholas Dionne-OdomSchool of Nursing, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. Electronic address: dionneod@uab.edu.
University of Alabama at Birmingham · USEmory University · USBoston Children's Hospital · USNew York University · USNorthwestern University · USO'Neal Comprehensive Cancer CenterUniversity of Alabama · US

Funding

Investigator Development CoreP50MD017338 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M · 2021 to 2025
$27.7M
Decision Support Training for Advanced Cancer Family Caregivers: The CASCADE Factorial TrialR01CA262039 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ODOM, JAMES N. · 2021 to 2025
$2.9M
Optimizing an Early Palliative Care Intervention for Advanced HF PatientsK99NR019854 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WELLS, RACHEL D · 2021 to 2022
$174k
NCI NIH HHS R01 CA262039NIMHD NIH HHS P50 MD017338NINR NIH HHS K99 NR019854
6 · The paper itself

Abstract

backgroundPatients with advanced cancer face numerous decisions when diagnosed and often receive decision support from family caregivers. The CASCADE (CAre Supporters Coached to be Adept DEcision partners) factorial trial intervention aims to train caregivers in skills to provide effective decision support to patients and identify most effective intervention components.

methodsThis is a 2-site, single-blind, 2 DISCUSSION: This protocol describes the first factorial trial, informed by the multiphase optimization strategy, of a palliative care decision-support intervention for advanced cancer family caregivers and will address the field's need to identify effective components that support serious illness decision-making.

trial registrationNCT04803604.

Indexed as

CaregiversNeoplasmsHumansPalliative CareQuality of LifeRandomized Controlled Trials as TopicSingle-Blind MethodcancerDecision-makingFactorial trialFamily caregiverMultiphase optimization strategy

Identifiers

PMID37286131
PMCPMC10527385
OpenAlexW4379382785

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.