Evidence map›Paper›PMID 37285605›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Hfq-licensed RNA-RNA interactome in

Michael J Gebhardt, Elizabeth A Farland, Pallabi Basu, Keven Macareno, Sahar Melamed, Simon L Dove

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Loss of CsrA inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. A genome-wide screen inJournal of bacteriology · 2026
    Article
  4. Review
  5. Article
  6. A bacterial translation activator with an intrinsically disordered RNA-binding region.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. What makes a small RNA work?Nucleic acids research · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Michael J GebhardtDivision of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-1213-8408
Elizabeth A FarlandDivision of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115.
Pallabi BasuDivision of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-8163-7518
Keven MacarenoDivision of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-3478-4195
Sahar MelamedDepartment of Microbiology and Molecular Genetics, Faculty of Medicine, Institute for Medical Research Israel-Canada, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.ORCID 0000-0003-1360-1297
Simon L DoveDivision of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-3758-608X
Boston Children's Hospital · USHebrew University of Jerusalem · IL

Funding

SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2M
Global post-transcriptional regulators in P. aeruginosaR01AI143771 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI SIMON L DOVE · 2020 to 2026
$4.3M
NIAID NIH HHS R01 AI143771NICHD NIH HHS P30 HD018655
6 · The paper itself

Abstract

The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the base pairing between small RNAs (sRNAs) and their cognate mRNA targets. In the gram-negative opportunistic pathogen

Indexed as

Pseudomonas aeruginosaRNA, Small UntranslatedBacteriaGene Expression Regulation, BacterialHost Factor 1 ProteinRNA, BacterialRNA, MessengerHost Factor 1 ProteinRNA, BacterialRNA, MessengerRNA, Small UntranslatedHfqPhrSposttranscriptional regulatorsmall RNA

Identifiers

PMID37285605
PMCPMC10214189
OpenAlexW4379768685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.