Evidence map›Paper›PMID 37285547›Full record

ArticleBiochemistry2023

A Single DNA Point Mutation Leads to the Formation of a Cysteine-Tyrosine Crosslink in the Cysteine Dioxygenase from

Rebecca L Schultz, Grzegorz Sabat, Brian G Fox, Thomas C Brunold

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rebecca L SchultzDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Grzegorz SabatMass Spectrometry Core, Biotechnology Center, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Brian G FoxDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Thomas C BrunoldDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0001-6516-598X
University of Wisconsin–Madison · US

Funding

Structure/Function Relationships in Cysteine and Cysteamine DioxygenasesR01GM117120 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BRUNOLD, THOMAS CHRISTIAN · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM117120
6 · The paper itself

Abstract

Cysteine dioxygenase (CDO) is a non-heme iron-containing enzyme that catalyzes the oxidation of cysteine (Cys) to cysteine sulfinic acid (CSA). Crystal structures of eukaryotic CDOs revealed the presence of an unusual crosslink between the sulfur of a cysteine residue (C93 in

Indexed as

Bacillus subtilisCysteineCysteine DioxygenaseAnimalsKineticsMicePoint MutationTyrosineCysteineCysteine DioxygenaseTyrosine

Identifiers

PMID37285547
PMCPMC10697556
OpenAlexW4379744612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.