Evidence map›Paper›PMID 37285423›Full record

ArticleScience advances2023

Origin of biological homochirality by crystallization of an RNA precursor on a magnetic surface.

S Furkan Ozturk, Ziwei Liu, John D Sutherland, Dimitar D Sasselov

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Temperature-Enhanced Coercive Field by Chiral Molecules.The journal of physical chemistry letters · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Origin of Single-Molecule Reaction Chirality.Research (Washington, D.C.) · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Life's homochirality: Across a prebiotic network.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Stereoselectivity of Aminoacyl-RNA Loop-Closing Ligation.Journal of the American Chemical Society · 2025
    Article
  17. Article
  18. Article
  19. Primitive homochiral polyester formation driven by tartaric acid and calcium availability.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Chiral Phonons Enhance Ferromagnetism.The journal of physical chemistry letters · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S Furkan OzturkDepartment of Physics, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-1830-3619
Ziwei LiuMRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.ORCID 0000-0002-1812-2538
John D SutherlandMRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.ORCID 0000-0001-7099-4731
Dimitar D SasselovDepartment of Astronomy, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-7014-1771

Funding

Medical Research Council MC_UP_A024_1009
6 · The paper itself

Abstract

Homochirality is a signature of life on Earth, yet its origins remain an unsolved puzzle. Achieving homochirality is essential for a high-yielding prebiotic network capable of producing functional polymers like RNA and peptides on a persistent basis. Because of the chiral-induced spin selectivity effect, which established a strong coupling between electron spin and molecular chirality, magnetic surfaces can act as chiral agents and be templates for the enantioselective crystallization of chiral molecules. Here, we studied the spin-selective crystallization of racemic ribo-aminooxazoline (RAO), an RNA precursor, on magnetite (Fe

Indexed as

Ferrosoferric OxideRNA PrecursorsCrystallizationElectronsRNAStereoisomerismFerrosoferric OxideRNARNA Precursors

Identifiers

PMID37285423
PMCPMC10246896

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.