Evidence map›Paper›PMID 37285304›Full record

ArticleChemical communications (Cambridge, England)2023

A high-performance electrochemical biosensor using an engineered urate oxidase.

Zheng Wei, Tanja Knaus, Yuxin Liu, Ziran Zhai, Andrea F G Gargano, Gadi Rothenberg, Ning Yan, Francesco G Mutti

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zheng WeiVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0002-3143-4720
Tanja KnausVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0001-9942-9226
Yuxin LiuVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0002-2080-487X
Ziran ZhaiVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.
Andrea F G GarganoVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0003-3361-7341
Gadi RothenbergVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0003-1286-4474
Ning YanVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0001-6677-7507
Francesco G MuttiVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. f.mutti@uva.nl.ORCID http://orcid.org/0000-0002-6771-5102
University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We constructed a high-performance biosensor for detecting uric acid by immobilizing an engineered urate oxidase on gold nanoparticles deposited on a carbon-glass electrode. This biosensor showed a low limit-of-detection (9.16 nM), a high sensitivity (14 μA/μM), a wide range of linearity (50 nM-1 mM), and more than 28 days lifetime.

Indexed as

Biosensing TechniquesMetal NanoparticlesCarbonElectrochemical TechniquesElectrodesEnzymes, ImmobilizedGoldUrate OxidaseCarbonEnzymes, ImmobilizedGoldUrate Oxidase

Identifiers

PMID37285304
PMCPMC10297830
OpenAlexW4379768578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.