Evidence map›Paper›PMID 37285134›Full record

ArticleJournal of medicinal chemistry2023

Hydrogel-Encapsulated Biofilm Inhibitors Abrogate the Cariogenic Activity of

Parmanand Ahirwar, Veronika Kozlovskaya, Bhavitavya Nijampatnam, Edwin M Rojas, Piyasuda Pukkanasut, Daniel Inman, Maksim Dolmat, Anna C Law, Norbert Schormann, Champion Deivanayagam and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Polymer vesicles for the delivery of inhibitors of cariogenic biofilm.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Parmanand Ahirwar
Veronika KozlovskayaORCID 0000-0001-9089-4842
Bhavitavya Nijampatnam
Edwin M Rojas
Piyasuda Pukkanasut
Daniel Inman
Anna C Law
Norbert Schormann
Champion Deivanayagam
Gregory J Harber
Suzanne M Michalek
Hui WuDepartment of Integrative Biomedical and Diagnostic Sciences, Oregon Health and Science University, Portland, Oregon 97239, United States.
Eugenia KharlampievaORCID 0000-0003-0227-0920
Sadanandan E VeluORCID 0000-0002-0342-2378
University of Alabama at Birmingham · USOregon Health & Science University · US

Funding

SMALL MOLECULE INHIBITORS OF CARIOGENIC BIOFILMSR01DE022350 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Christian Corey Melander, Hui Wu · 2012 to 2026
$4.3M
Hydrogel encapsulated biofilm inhibitors for dental caries prevention and treatmentR21DE028349 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VELU, SADANANDAN E. · 2019 to 2020
$396k
S. mutans GTF - a novel target for dental caries preventionR03DE025058 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VELU, SADANANDAN E. · 2015 to 2016
$221k
Streptococcus mutans diadenylate cyclase: A promising target for preventing dental cariesF30DE030334 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROJAS, EDWIN M · 2020 to 2024
$212k
Polyphenolic inhibitors of S. Mutans glucosyltransferases to fight dental cariesF31DE025783 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NIJAMPATNAM, BHAVITAVYA · 2016 to 2017
$66k
NIDCR NIH HHS F30 DE030334NIDCR NIH HHS F31 DE025783NIDCR NIH HHS R01 DE022350NIDCR NIH HHS R03 DE025058NIDCR NIH HHS R21 DE028349
6 · The paper itself

Abstract

We designed and synthesized analogues of a previously identified biofilm inhibitor

Indexed as

Dental CariesStreptococcus mutansAnimalsBiofilmsHydrogelsRatsHydrogels

Identifiers

PMID37285134
PMCPMC11188996
OpenAlexW4379598144

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.