Evidence map›Paper›PMID 37284977›Full record

ArticleNeuroinformatics2023

Geometric Reliability of Super-Resolution Reconstructed Images from Clinical Fetal MRI in the Second Trimester.

Tommaso Ciceri, Letizia Squarcina, Alessandro Pigoni, Adele Ferro, Florian Montano, Alessandra Bertoldo, Nicola Persico, Simona Boito, Fabio Maria Triulzi, Giorgio Conte and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Neuroinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. MRI-based spatio-temporal atlas of ganglionic eminence.European radiology experimental · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Tommaso CiceriNeuroImaging Laboratory, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy.
Letizia SquarcinaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Alessandro PigoniSocial and Affective Neuroscience Group, IMT School for Advanced Studies Lucca, Lucca, Italy.
Adele FerroDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Florian MontanoNeuroImaging Laboratory, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy.
Alessandra BertoldoDepartment of Information Engineering, University of Padua, Padua, Italy.
Nicola PersicoDepartment of Woman, Child and Newborn, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Simona BoitoDepartment of Woman, Child and Newborn, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Fabio Maria TriulziDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Giorgio ConteDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Paolo BrambillaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy. paolo.brambilla1@unimi.it.
Denis PeruzzoNeuroImaging Laboratory, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fetal Magnetic Resonance Imaging (MRI) is an important noninvasive diagnostic tool to characterize the central nervous system (CNS) development, significantly contributing to pregnancy management. In clinical practice, fetal MRI of the brain includes the acquisition of fast anatomical sequences over different planes on which several biometric measurements are manually extracted. Recently, modern toolkits use the acquired two-dimensional (2D) images to reconstruct a Super-Resolution (SR) isotropic volume of the brain, enabling three-dimensional (3D) analysis of the fetal CNS.We analyzed 17 fetal MR exams performed in the second trimester, including orthogonal T2-weighted (T2w) Turbo Spin Echo (TSE) and balanced Fast Field Echo (b-FFE) sequences. For each subject and type of sequence, three distinct high-resolution volumes were reconstructed via NiftyMIC, MIALSRTK, and SVRTK toolkits. Fifteen biometric measurements were assessed both on the acquired 2D images and SR reconstructed volumes, and compared using Passing-Bablok regression, Bland-Altman plot analysis, and statistical tests.Results indicate that NiftyMIC and MIALSRTK provide reliable SR reconstructed volumes, suitable for biometric assessments. NiftyMIC also improves the operator intraclass correlation coefficient on the quantitative biometric measures with respect to the acquired 2D images. In addition, TSE sequences lead to more robust fetal brain reconstructions against intensity artifacts compared to b-FFE sequences, despite the latter exhibiting more defined anatomical details.Our findings strengthen the adoption of automatic toolkits for fetal brain reconstructions to perform biometry evaluations of fetal brain development over common clinical MR at an early pregnancy stage.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingBrainFemaleHumansPregnancyPregnancy Trimester, SecondReproducibility of ResultsFetal biometryFetal brainMagnetic Resonance ImagingPediatric ImagingSuper-Resolution Algorithm

Identifiers

PMID37284977
PMCPMC10406722

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.