Evidence map›Paper›PMID 37284828›Full record

ReviewAnatolian journal of cardiology2023

Obstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?

Yüksel Peker, Bahri Akdeniz, Servet Altay, Baran Balcan, Özcan Başaran, Erkan Baysal, Ahmet Çelik, Dursun Dursunoğlu, Neşe Dursunoğlu, Selma Fırat and 4 more

Open access · diamondAbstract readReview
In one paragraph

Review in Anatolian journal of cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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  4. Validation of a deep learning-based system for sleep staging, arousal detection, and respiratory event scoring in atrial fibrillation patients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yüksel PekerDepartment of Pulmonary Medicine, Koç University Faculty of Medicine, İstanbul, Turkey; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Bahri AkdenizDepartment of Cardiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.
Servet AltayDepartment of Cardiology, Trakya University Faculty of Medicine, Edirne, Turkey.
Baran BalcanDepartment of Pulmonary Medicine, Koç University Faculty of Medicine, İstanbul, Turkey.
Özcan BaşaranDepartment of Cardiology, Muğla Sıtkı Koçman University Faculty of Medicine, Muğla, Turkey.
Erkan BaysalDepartment of Cardiology, University of Health Sciences, Diyarbakır Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Ahmet ÇelikDepartment of Cardiology, Mersin University Faculty of Medicine, Mersin, Turkey.
Dursun DursunoğluDepartment of Cardiology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Neşe DursunoğluDepartment of Pulmonary Medicine, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Selma FıratDepartment of Pulmonary Medicine, University of Health Sciences, Atatürk Sanatorium Training and Research Hospital, Ankara, Turkey.
Canan Gündüz GürkanDepartment of Pulmonary Medicine, Süreyyapaşa Chest Diseases Training and Research Hospital, İstanbul, Turkey.
Önder ÖztürkDepartment of Pulmonary Medicine, Süleyman Demirel University Faculty of Medicine, Isparta, Turkey.
Mehmet Sezai TaşbakanDepartment of Pulmonary Medicine, Ege University Faculty of Medicine, İzmir, Turkey.
Vedat AytekinDepartment of Cardiology, Koç University Faculty of Medicine, İstanbul, Turkey.
University of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea is common in adults with cardiovascular disease. Accumulating evidence suggests an association between obstructive sleep apnea and cardiovascular disease independent of the traditionally recognized cardiovascular disease risk factors. Observational studies indicate that obstructive sleep apnea is a risk factor for development of cardiovascular disease and that alleviation of obstructive events with positive airway pressure may improve cardiovascular disease outcomes. However, recent randomized controlled trials have not supported the beneficial effect of positive airway pressure in cardiac populations with concomitant obstructive sleep apnea. Some evidence suggests that the relationship between obstructive sleep apnea and traditionally recognized cardiovascular disease risk factors is bidirectional, suggesting that patients with cardiovascular disease may also develop obstructive sleep apnea and that efficient treatment of cardiovascular disease may improve obstructive sleep apnea. Recent data also indicate that the apnea-hypopnea index, which is commonly used as a diagnostic measure of obstructive sleep apnea severity, has limited value as a prognostic measure for cardiovascular disease outcomes. Novel markers of obstructive sleep apnea-associated hypoxic burden and cardiac autonomic response seem to be strong predictors of adverse cardiovascular disease outcomes and response to treatment of obstructive sleep apnea. This narrative review and position paper from the Turkish Collaboration of Sleep Apnea Cardiovascular Trialists aims to update the current evidence about the relationship between obstructive sleep apnea and cardiovascular disease and, consequently, raise awareness for health professionals who deal with cardiovascular and respiratory diseases to improve the ability to direct resources at patients most likely to benefit from treatment of obstructive sleep apnea and optimize treatment of the coexisting cardiovascular diseases. Moreover, the Turkish Collaboration of Sleep Apnea Cardiovascular Trialists aims to contribute to strengthening the efforts of the International Collaboration of Sleep Apnea Cardiovascular Trialists in this context.

Indexed as

Cardiovascular DiseasesCardiovascular SystemSleep Apnea, ObstructiveSleep Apnea SyndromesAdultContinuous Positive Airway PressureHumansRisk Factors

Identifiers

PMID37284828
PMCPMC10339137
OpenAlexW4368240721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.