Evidence map›Paper›PMID 37284655›Full record

ArticleBiomaterials and biosystems2023

Electrochemical and in vitro biological behaviors of a Ti-Mo-Fe alloy specifically designed for stent applications.

Carolina Catanio Bortolan, Francesco Copes, Masoud Shekargoftar, Vinicius de Oliveira Fidelis Sales, Carlo Paternoster, Leonardo Contri Campanelli, Nicolas Giguère, Diego Mantovani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials and biosystems, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Carolina Catanio BortolanLaboratory for Biomaterials and Bioengineering (LBB). Canada Research Chair Tier I for the Innovation in Surgery, Department of Mining, Metallurgy, and Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval University, Quebec City G1V 0A6, Canada.
Francesco CopesLaboratory for Biomaterials and Bioengineering (LBB). Canada Research Chair Tier I for the Innovation in Surgery, Department of Mining, Metallurgy, and Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval University, Quebec City G1V 0A6, Canada.
Masoud ShekargoftarLaboratory for Biomaterials and Bioengineering (LBB). Canada Research Chair Tier I for the Innovation in Surgery, Department of Mining, Metallurgy, and Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval University, Quebec City G1V 0A6, Canada.
Vinicius de Oliveira Fidelis SalesLaboratory for Biomaterials and Bioengineering (LBB). Canada Research Chair Tier I for the Innovation in Surgery, Department of Mining, Metallurgy, and Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval University, Quebec City G1V 0A6, Canada.
Carlo PaternosterLaboratory for Biomaterials and Bioengineering (LBB). Canada Research Chair Tier I for the Innovation in Surgery, Department of Mining, Metallurgy, and Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval University, Quebec City G1V 0A6, Canada.
Leonardo Contri CampanelliInstitute of Science and Technology (ICT), Federal University of São Paulo - UNIFESP, São José dos Campos 12231-280, Brazil.
Nicolas GiguèreQuebec Metallurgy Center (CMQ), Trois-Rivières G9A 5E1, Canada.
Diego MantovaniLaboratory for Biomaterials and Bioengineering (LBB). Canada Research Chair Tier I for the Innovation in Surgery, Department of Mining, Metallurgy, and Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval University, Quebec City G1V 0A6, Canada.
Université Laval · CAUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a deep interest in developing new Ni-free Ti-based alloys to replace 316 L stainless steel and Co-Cr alloys for endovascular stent application, mainly because the release of Ni can generate toxicity and allergenicity. Interactions of Ti alloy biomaterials with bone cells and tissues have been widely investigated and reported, while interactions with vascular cells and tissues, such as endothelial cells (ECs) and smooth muscle cells (SMCs), are scarce. Therefore, this study focused on the relationship among the surface finishing features, corrosion behavior and in vitro biological performances regarding human ECs, SMCs and blood of a newly developed Ti-8Mo-2Fe (TMF) alloy, specifically designed for balloon-expandable stent applications. The alloy performances were compared to those of 316 L and pure Ti, prepared with the same surface finishing techniques, which are mechanical polishing and electropolishing. Surface properties were investigated by scanning electron microscopy (SEM), atomic force microscopy (AFM), contact angle (CA) and x-ray photoelectron spectroscopy (XPS). The corrosion behavior was assessed with potentiodynamic polarization (PDP) and electrochemical impedance spectroscopy (EIS) tests in phosphate buffered saline (PBS) solution. No significant differences were observed regarding the corrosion rate measured with PDP analyses, which was of the order of 2 × 10

Indexed as

CorrosionEndothelial cellsHemocompatibilitySmooth muscle cellsStentsTitanium alloy

Identifiers

PMID37284655
PMCPMC10240522
OpenAlexW4360977337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.