Evidence map›Paper›PMID 37284443›Full record

ArticleTheranostics2023

Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution.

Li Han, Xinran Wu, Ou Wang, Xiao Luan, William H Velander, Michael Aynardi, E Scott Halstead, Anthony S Bonavia, Rong Jin, Guohong Li and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Li HanDepartment of Biomedical Engineering, Pennsylvania State University; University Park, PA, 16802, USA.
Xinran WuDepartment of Biomedical Engineering, Pennsylvania State University; University Park, PA, 16802, USA.
Ou WangDepartment of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln; Lincoln, NE, 68588, USA.
Xiao LuanBiomedical Center of Qingdao University; Qingdao, Shandong, 266000, China.
William H VelanderDepartment of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln; Lincoln, NE, 68588, USA.
Michael AynardiDepartment of Orthopedics Surgery, Pennsylvania State University College of Medicine; Hershey, PA, 17033, USA.
E Scott HalsteadDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Pennsylvania State Milton S Hershey Medical Center; Hershey, PA, 17033, USA.
Anthony S BonaviaDivision of Critical Care Medicine, Department of Anesthesiology and Perioperative Medicine, Pennsylvania State Milton S Hershey Medical Center; Hershey, PA, 17033, USA.
Rong JinDepartment of Neurosurgery, Pennsylvania State Milton S Hershey Medical Center; Hershey, PA, 17033, USA.
Guohong LiDepartment of Neurosurgery, Pennsylvania State Milton S Hershey Medical Center; Hershey, PA, 17033, USA.
Yulong LiDepartment of Emergency Medicine, University of Nebraska Medical Center; Omaha, NE, 68105, USA.
Yong WangDepartment of Biomedical Engineering, Pennsylvania State University; University Park, PA, 16802, USA.
Cheng DongDepartment of Biomedical Engineering, Pennsylvania State University; University Park, PA, 16802, USA.
Yuguo LeiDepartment of Biomedical Engineering, Pennsylvania State University; University Park, PA, 16802, USA.
Penn State Milton S. Hershey Medical Center · USPennsylvania State University · USUniversity of Nebraska–Lincoln · USQingdao Center of Resource Chemistry and New Materials · CNUniversity of Nebraska Medical Center · US

Funding

Mechanisms of cardiac sympathetic hyperactivity in chronic heart failureR01HL137832 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Yu-Long Li · 2017 to 2026
$4.1M
Neuromuscular junction as a therapeutic target to improve post-traumatic outcomesR01GM145736 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LI, YU-LONG · 2022 to 2025
$1.5M
A Single Conical Tube Device for Precision CAR-T Cells ManufacturingR33CA235326 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI LEI, YUGUO · 2019 to 2021
$1.1M
An Enabling Technology for Human Cardiomyocyte ManufacturingR33HL163711 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI LEI, YUGUO · 2022 to 2023
$809k
Resistin-induced immunosuppression increases susceptibility to infectious lung injury and sepsis during AKIK08GM138825 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BONAVIA, ANTHONY S · 2020 to 2022
$604k
NCI NIH HHS R33 CA235326NHLBI NIH HHS R01 HL137832NHLBI NIH HHS R33 HL163711NIGMS NIH HHS K08 GM138825
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsCell LineCytokinesInflammationMiceReactive Oxygen SpeciesCytokinesReactive Oxygen Speciesalpha-1 antitrypsincombination therapyinflammationmesenchymal stromal cells

Identifiers

PMID37284443
PMCPMC10240832
OpenAlexW4379600170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.