Evidence map›Paper›PMID 37284303›Full record

ArticleFrontiers in pharmacology2023

SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in

Silvia Romero-Sanz, Elena Caldero-Escudero, Pilar Álvarez-Illera, Jaime Santo-Domingo, Rosalba I Fonteriz, Mayte Montero, Javier Álvarez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Rescue of a Rotenone Model of Parkinson's Disease inInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Silvia Romero-SanzDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Elena Caldero-EscuderoDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Pilar Álvarez-IlleraDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Jaime Santo-DomingoDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Rosalba I FonterizDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Mayte MonteroDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Javier ÁlvarezDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Unidad de Excelencia Instituto de Biomedicina y Genética Molecular (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Instituto de Biomedicina y Genética Molecular de Valladolid · ESUniversidad de Valladolid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ca2+ signalingC. elegansendoplasmic reticulumlifespanmitochondriaParkinson’s diseaserotenoneSERCA

Identifiers

PMID37284303
PMCPMC10239880
OpenAlexW4377206072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.