ArticleQuantitative imaging in medicine and surgery2023
Value of spectral computed tomography-derived quantitative parameters based on full volume analysis in the diagnosis of benign/malignant and pathological subtypes of solitary pulmonary nodules.
Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 5 citations in OpenAlex.
- Noninvasive differentiation of benign and malignant solid pulmonary nodules using multiparameter dual-layer spectral CT radiomics.Insights into imaging · 2026Article
- The added value of quantitative contrast-enhanced CT parameters in distinguishing malignant from benign solid pulmonary nodules.BMC medical imaging · 2025Article
- Utilizing spectral detector computed tomography quantitative parameters via multimodality tumor tracking to predict occult lymph node metastasis in clinical stage 1 pure solid lung adenocarcinoma.Journal of thoracic disease · 2025Article
- Predictive value of spectral dual-detector computed tomography forQuantitative imaging in medicine and surgery · 2024Article
- Value of dual-layer spectral detector CT in predicting lymph node metastasis of non-small cell lung cancer.Quantitative imaging in medicine and surgery · 2024Article
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8 authors at 2 institutions in 1 country.
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Abstract
Background: Conventional dynamic computed tomography (CT) has a low specificity for the distinction between benign and malignant solitary pulmonary nodules (SPNs), and spectral CT has been proposed as a potential alternative. We aimed to investigate the role of quantitative parameters based on full-volume spectral CT in the differential diagnosis of SPNs. Methods: This retrospective study included spectral CT images of 100 patients with pathologically confirmed SPNs (78 and 22 in the malignant and benign groups, respectively). All cases were confirmed by postoperative pathology, percutaneous biopsy, and bronchoscopic biopsy. Multiple quantitative parameters derived from spectral CT were extracted from whole-tumor volume and standardized. Differences in quantitative parameters between groups were statistically analyzed. Diagnostic efficiency was evaluated by generating a receiver operating characteristic (ROC) curve. Between-group differences were evaluated using an independent sample Results: Spectral CT-derived quantitative parameters, except attenuation difference between the SPN in the 70 keV and arterial enhancement [Δ Conclusions: Our study suggests that quantitative parameters derived from whole-volume spectral CT may be useful to improve discrimination of SPNs.
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