Evidence map›Paper›PMID 37283798›Full record

ArticleJournal of Cancer2023

APEX1 predicts poor prognosis of gallbladder cancer and affects biological properties of CD133

Zhengchun Wu, Ziru Liu, Yi Sun, Yuan Yuan, Qiong Zou, Yun Wen, Jia Luo, Rushi Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Research progress on prognostic factors of gallbladder carcinoma.Journal of cancer research and clinical oncology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Zhengchun WuDepartment of Hepatobiliary and Intestinal Surgery, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan410013, China.
Ziru LiuDepartment of General Surgery, Second Xiangya Hospital, Central South University, Changsha, Hunan410011, China.
Yi SunDepartment of Pathology, Second Xiangya Hospital, Central South University, Changsha, Hunan410011, China.
Yuan YuanDepartment of Pathology, Third Xiangya Hospital, Central South University, Changsha, Hunan410013, China.
Qiong ZouDepartment of Pathology, Third Xiangya Hospital, Central South University, Changsha, Hunan410013, China.
Yun WenDepartment of General Surgery, Second Xiangya Hospital, Central South University, Changsha, Hunan410011, China.
Jia LuoDepartment of Hepatobiliary and Intestinal Surgery, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan410013, China.
Rushi LiuLaboratory of Medical Molecular and Immunological Diagnostics, School of medicine, Hunan Normal University, Changsha, Hunan 410013, China.
Hunan Cancer Hospital · CNSecond Xiangya Hospital of Central South University · CNThird Xiangya Hospital · CNCentral South University · CNHunan Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although APEX1 is associated with the tumorigenesis and progression of some human cancer types, the function of APEX1 in gallbladder cancer (GBC) is unclear. In this study, we found that APEX1 expression is up-regulated in GBC tissues, and APEX1 positive expression is related to aggressive clinicopathological features and poor prognosis of GBC. APEX1 was an independent risk factor of GBC prognosis, and presented some pathological diagnostic significance in GBC. Furthermore, APEX1 was overexpressed in CD133

Indexed as

APEX1CD133+ cancer cellsGallbladder cancerJagged1Prognosis

Identifiers

PMID37283798
PMCPMC10240672
OpenAlexW4379599531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.