Evidence map›Paper›PMID 37283722›Full record

ArticleOptica2022

Flexible method for generating needle-shaped beams and its application in optical coherence tomography.

Jingjing Zhao, Yonatan Winetraub, Lin DU, Aidan VAN Vleck, Kenzo Ichimura, Cheng Huang, Sumaira Z AAsI, Kavita Y Sarin, Adam DE LA Zerda

Open access · goldAbstract read
In one paragraph

Article in Optica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  6. Metalens for passive generation of a droplet Bessel beam.Microsystems & nanoengineering · 2025
    Article
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  11. Review
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  17. ImprovedJournal of biomedical optics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jingjing ZhaoDepartment of Structural Biology, Stanford University School ofMedicine, Stanford, California 94305, USA.
Yonatan WinetraubDepartment of Structural Biology, Stanford University School ofMedicine, Stanford, California 94305, USA.
Lin DUDepartment ofElectrical and Systems Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Aidan VAN VleckDepartment of Structural Biology, Stanford University School ofMedicine, Stanford, California 94305, USA.
Kenzo IchimuraDivision of Pulmonary, Allergy and Critical Care, Stanford University School ofMedicine, Stanford, California 94305, USA.
Cheng HuangDepartment of Biology, Stanford University, Stanford, California 94305, USA.
Sumaira Z AAsIDepartment of Dermatology, Stanford University School of Medicine, Stanford, California 94305, USA.
Kavita Y SarinDepartment of Dermatology, Stanford University School of Medicine, Stanford, California 94305, USA.
Adam DE LA ZerdaDepartment of Structural Biology, Stanford University School ofMedicine, Stanford, California 94305, USA.
Stanford University · USCalifornia University of Pennsylvania · USChan Zuckerberg Initiative (United States) · US

Funding

Pilot ProjectsU54CA151459 · NCI · STANFORD UNIVERSITY · PI SINCLAIR, ROBERT · 2010 to 2014
$12.6M
Repurposing systemic therapies to improve clinical outcomes in advanced basal cell cancerK23CA211793 · NCI · STANFORD UNIVERSITY · PI SARIN, KAVITA YANG · 2018 to 2022
$868k
NCI NIH HHS K23 CA211793NCI NIH HHS U54 CA151459
6 · The paper itself

Abstract

Needle-shaped beams (NBs) featuring a long depth-of-focus (DOF) can drastically improve the resolution of microscopy systems. However, thus far, the implementation of a specific NB has been onerous due to the lack of a common, flexible generation method. Here we develop a spatially multiplexed phase pattern that creates many axially closely spaced foci as a universal platform for customizing various NBs, allowing flexible manipulations of beam length and diameter, uniform axial intensity, and sub-diffraction-limit beams. NBs designed via this method successfully extended the DOF of our optical coherence tomography (OCT) system. It revealed clear individual epidermal cells of the entire human epidermis, fine structures of human dermal-epidermal junction in a large depth range, and a high-resolution dynamic heartbeat of alive

Identifiers

PMID37283722
PMCPMC10243785
OpenAlexW4283388860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.