Evidence map›Paper›PMID 37283716›Full record

ArticleMedical mycology case reports2023

Persistently elevated intracranial pressure in cryptococcal meningitis- 76 therapeutic lumbar punctures.

Samuel Jjunju, Edwin Nuwagira, David B Meya, Conrad Muzoora

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical mycology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Comparison of Early Fungicidal Activity and Mortality Between Daily Liposomal Amphotericin B and Daily Amphotericin B Deoxycholate for Cryptococcal Meningitis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  4. Review
  5. Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel JjunjuDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Edwin NuwagiraDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
David B MeyaResearch Department, Infectious Disease Institute, Makerere University, Kampala, Uganda.
Conrad MuzooraDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcal meningitis still remains the most common form of adult meningitis in sub-Saharan Africa, due to the burden of HIV/AIDS. Increased intracranial pressure (ICP) is a major complication of cryptococcosis and requires aggressive management with therapeutic lumbar punctures (LPs). In this report, we describe a patient with persistently elevated ICP who underwent 76 LPs over 46 days with good outcome. While unusual, this highlights the importance of serial therapeutic LPs. 2012 Elsevier Ltd. All rights reserved.

Indexed as

Cryptococcal meningitisHuman Immunodeficiency VirusIncreased intracranial pressureLumbar puncture

Identifiers

PMID37283716
PMCPMC10240505

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.