Evidence map›Paper›PMID 37283668›Full record

ArticleFree neuropathology2020

Treatment of autoimmune encephalomyelitis with a histone deacetylase inhibitor.

Arathi K Jayaraman, Karen Avgush, Rashad Kulam, Advait Soni, Areeb Khan, Mourad Kerdjoudj, Sundararajan Jayaraman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Free neuropathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Arathi K JayaramanDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
Karen AvgushDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
Rashad KulamDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
Advait SoniDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
Areeb KhanDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
Mourad KerdjoudjDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
Sundararajan JayaramanDept. of Microbiology and Immunology, the University of Illinois at Chicago USA.
University of Illinois Chicago · USIllinois College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that treatment of female NOD mice with a potent nonselective histone deacetylase inhibitor attenuated experimental autoimmune encephalomyelitis, a model for progressive multiple sclerosis. Herein we show that immunization with the MOG

Indexed as

Autoreactive T cellsEpigenetic regulationExperimental autoimmune encephalomyelitisGene expressionMultiple sclerosisTrichostatin A

Identifiers

PMID37283668
PMCPMC10240938
OpenAlexW3044001553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.