Evidence map›Paper›PMID 37283467›Full record

ArticleThe Laryngoscope2023

The Application of Ultrasound to Quantify Hyoid Motion During Drug-Induced Sleep Endoscopy.

Manan H Parekh, Eric Thuler, Vasiliki Triantafillou, Everett Seay, Chandra Sehgal, Susan Schultz, Brendan T Keenan, Alan R Schwartz, Raj C Dedhia

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. [Dynamic assessment of upper airway in obstructive sleep apnea patients with a focus on drug-induced sleep endoscopy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Ascending and Descending Pharyngeal Opening Pressures During Drug-Induced Sleep Endoscopy: Mechanistic Insights for Sleep Surgeons.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Manan H ParekhDepartment of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7528-6910
Eric ThulerDepartment of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Vasiliki TriantafillouDepartment of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-6112-8361
Everett SeayDepartment of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Chandra SehgalDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Susan SchultzDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Brendan T KeenanDivision of Sleep Medicine/Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Alan R SchwartzDepartment of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Raj C DedhiaDepartment of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-5568-0427
University of Pennsylvania · US

Funding

Lingual muscle control of upper airway patency in obstructive sleep apneaR01HL144859 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DEDHIA, RAJ C., SCHWARTZ, ALAN R. · 2019 to 2023
$3.9M
NHLBI NIH HHS R01 HL144859
6 · The paper itself

Abstract

introductionThe significance of hyoid dynamics in OSA pathophysiology remains unclear. Drug-induced sleep endoscopy (DISE) is often used for evaluating patients intolerant to positive airway pressure (PAP) therapy. We performed DISE with concurrent hyoid-focused ultrasonography to quantify hyoid dynamics during obstructive and non-obstructive breathing.

methodsA cross-sectional analysis from a prospective cohort of patients undergoing DISE with PAP titration (DISE-PAP) and hyoid-focused ultrasound was conducted. Hyoid ultrasound was performed during obstructive breathing, and non-obstructive breathing after PAP administration. Motion was quantified by generating displacement curves based on echo-tracking hyoid movement. The image analysis protocol for quantifying hyoid displacement was performed independently by two researchers, and reliability of measures was assessed. Univariate and multivariate regressions were performed for various clinical data and hyoid displacement during obstructive breathing.

resultsTwenty patients met inclusion criteria. On average, the cohort was male (75%), elderly (65.9 ± 10 years), overweight (29.3 ± 3.99 kg/m

conclusionDuring DISE, hyoid displacement is greater during obstructive breathing with significant variability amongst patients. Further, these ultrasonographic measurements had excellent intra- and inter-rater reliability. Additional, larger studies are needed to understand contributors to hyoid mobility. LEVEL OF EVIDENCE: 4 Laryngoscope, 133:3221-3227, 2023.

Indexed as

Sleep Apnea, ObstructiveAgedCross-Sectional StudiesEndoscopyHumansMalePolysomnographyProspective StudiesReproducibility of ResultsSleepUltrasonographyhyoidObstructive sleep apneasleep endoscopyultrasound

Identifiers

PMID37283467
PMCPMC10592545
OpenAlexW4379598741

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.