Evidence map›Paper›PMID 37283252›Full record

ArticleCancer medicine2023

Financial well-being as a mediator of the relationship between multimorbidity and health-related quality of life in people with cancer.

Winnie K W So, Doreen W H Au, Dorothy N S Chan, Marques S N Ng, Kai Chow Choi, Weijie Xing, Mandy Chan, Suzanne S S Mak, Pui Shan Ho, Man Tong and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Winnie K W SoThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-9243-2924
Doreen W H AuThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-3793-5331
Dorothy N S ChanThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-6848-9947
Marques S N NgThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-1520-1783
Kai Chow ChoiThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-7157-8668
Weijie XingSchool of Nursing, Fudan University, Shanghai, China.
Mandy ChanDepartment of Clinical Oncology, Prince of Wales Hospital, Hong Kong, China.
Suzanne S S MakDepartment of Clinical Oncology, Prince of Wales Hospital, Hong Kong, China.
Pui Shan HoDepartment of Clinical Oncology, Tuen Mun Hospital, Hong Kong, China.
Man TongDepartment of Clinical Oncology, Tuen Mun Hospital, Hong Kong, China.
Cecilia AuDepartment of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Wai Man LingDepartment of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Maggie ChanTung Wah Eastern Hospital, Hong Kong, China.
Raymond J ChanCaring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, Australia.
Chinese University of Hong Kong · HKPamela Youde Nethersole Eastern Hospital · CNTuen Mun Hospital · CNTung Wah Eastern Hospital · CNFlinders University · AUFudan University · CNPrince of Wales Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is unknown whether financial well-being mediates the impact of multimorbidity on the health-related quality of life (HRQoL) of cancer patients.

methodsParticipants were recruited from three outpatient oncology clinics of Hong Kong public hospitals. Multimorbidity was assessed using the Charlson Comorbidity Index. Financial well-being, the mediator of the association between multimorbidity and HRQoL outcomes, was assessed using the Comprehensive Score for Financial Toxicity Functional Assessment of Chronic Illness Therapy. The HRQoL outcomes were assessed using the Functional Assessment of Cancer Therapy - General (FACT-G) and its four sub-dimensions. Mediation analyses were conducted using SPSS PROCESS v4.1.

resultsSix-hundred and forty cancer patients participated in the study. Multimorbidity had a direct effect on FACT-G scores independent of financial well-being (β for path c' = -0.752, p < 0.001). In addition, multimorbidity had an indirect effect on FACT-G scores through its effect on financial well-being (β for path a = -0.517, p < 0.05; β for path b = 0.785, p < 0.001). Even after adjustments were made for the covariates, the indirect effect of multimorbidity on FACT-G via financial well-being remained significant, accounting for 38.0% of the overall effect, indicating partial mediation. Although there were no statistically significant associations between multimorbidity, social well-being, and emotional well-being, the indirect effects of multimorbidity on physical and functional well-being through financial well-being remained significant.

conclusionsPoor financial well-being attributable to multimorbidity partially mediates the direct impact of chronic conditions on HRQoL in Chinese cancer patients, particularly their physical and functional well-being.

Indexed as

MultimorbidityNeoplasmsChronic DiseaseHumansMediation AnalysisQuality of Lifecancer patientsfinancial well-beingmultimorbidityquality of life

Identifiers

PMID37283252
PMCPMC10417171
OpenAlexW4379599020

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.