Evidence map›Paper›PMID 37282636›Full record

ArticlePharmaceutical nanotechnology2024

Fabrication and Synthesis of Thiococlchicoside Loaded Matrix Type Transdermal Patch.

Nishant Thakur, Manish Goswami, Asmita Deka Dey, Bhupinder Kaur, Chandan Sharma, Arun Kumar

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Article in Pharmaceutical nanotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nishant ThakurDepartment of Pharmaceutics, University Institute of Pharma Sciences, Chandigarh University, Gharuan Mohali, Punjab, 140413, India.
Manish GoswamiDepartment of Pharmaceutics, Saraswati College of Pharmacy, Gharuan, Mohali, Punjab, 140413, India.
Asmita Deka DeyDepartment of Pharmaceutics, Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Bhupinder KaurDepartment of Pharmaceutics, University Institute of Pharma Sciences, Chandigarh University, Gharuan Mohali, Punjab, 140413, India.
Chandan SharmaDepartment of Pharmaceutics, University Institute of Pharma Sciences, Chandigarh University, Gharuan Mohali, Punjab, 140413, India.
Arun KumarDepartment of Pharmaceutics, Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Chandigarh University · INCentral University of South Bihar · INChitkara University · INSaraswati Dental College and Hospital · IN

Funding

Department of Science and Technology SP/YO/063.
6 · The paper itself

Abstract

backgroundThe goal of this work was to synthesize and fabricate matrix type transdermal patches based on a combination of polymers (Eudragit L100, HPMC and PVP K30), plasticizer and crosslinking agents (propylene glycol and triethyl citrate) and adhesives (Dura Tak 87-6908) to increase Thiocolchicoside (THC) absorption

methodsFabrication and casting of polymeric solutions containing THC was done either in petri plates or through lab coater to get transdermal patches. Finally, the formulated patches were studied for their physicochemical and biological evaluation using scanning electron microscopy, FTIR, DSC, XRD and

resultsFTIR studies confirm that the THC characteristics peaks (carbonyl (Amide I) at 1525.5 cm

conclusionAll these findings support the possibility of using suitable polymeric composition, as well as proper formulation and manufacturing circumstances, to create a one-of-a-kind technology platform for transdermal drug administration.

Indexed as

Administration, CutaneousColchicineSkin AbsorptionTransdermal PatchAnimalsPlasticizersPolymersSkinSwineColchicinePlasticizersPolymersthiocolchicosideDSC studiesfull factorial design expertkinetics.polymersthiocolchicosideTransdermal delivery

Identifiers

PMID37282636
OpenAlexW4379600651

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.