ArticlePsychological medicine2023
Frequency and predictors of individual treatment outcomes (response, remission, exacerbation, and relapse) in clinical adolescents with nonsuicidal self-injury.
Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Integrating neurobiological markers to prospectively predict adolescent non-suicidal self-injury and suicide attempts: a machine learning approach.Child and adolescent psychiatry and mental health · 2026Article
- Psychological heterogeneity and transitions of non-suicidal self-injury in adolescents: a two-wave longitudinal cohort study.BMC psychiatry · 2026Article
- Accelerated Magnetic Seizure Therapy for Non-Suicidal Self-Injury in Adolescents With Bipolar Depression.CNS neuroscience & therapeutics · 2026Article
- Visualized Analysis of Adolescent Non-Suicidal Self-Injury and Comorbidity Networks.Behavioral sciences (Basel, Switzerland) · 2025Review
- First evaluation of the emotional picture set of self-injury images (EPSI) using psychophysiological and self-report measures.Borderline personality disorder and emotion dysregulation · 2025Article
- Symptom Shifting From Nonsuicidal Self-Injury to Substance Use and Borderline Personality Pathology.JAMA network open · 2024Article
- The Short-Term Course of Nonsuicidal Self-Injury Among Individuals Seeking Psychiatric Treatment.JAMA network open · 2024Article
- The evaluation of a stepped care approach for early intervention of borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNonsuicidal self-injury (NSSI) is prevalent in adolescent clinical samples. There is evidence that NSSI can be treated effectively but data on individual treatment outcomes is limited. The goal of this study was to examine response, remission, exacerbation, and relapse rates over one and two years, respectively, among a clinical sample of adolescents with NSSI. Furthermore, we aimed to identify clinically relevant predictors of NSSI trajectories.
methodsThe sample consists of
resultsAt FU1, 75% reported a reduction in NSSI frequency by at least 50% (treatment response); among those, one third (25% of the entire sample) achieved a remission (0 NSSI); an exacerbation (⩾50% more NSSI) was observed in 11% of patients. Of those in remission, 41% relapsed one year later. Predictors of non-response or non-remission were inpatient treatment and depressive symptoms. Adolescents with lower NSSI frequency at baseline had a higher risk of exacerbation. Due to limited sample size at FU2 no prediction model for relapse was established.
conclusionsWhile most adolescents presenting with NSSI achieved significant improvement, more attention should be paid to the rather low rates of full remission. Prediction and early detection of individuals who deteriorate during or relapse after treatment is critical.
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