Evidence map›Paper›PMID 37282308›Full record

ArticleDevelopment, growth & differentiation1995

Monolayer culture conditions suitable for primitive erythroid cell differentiation from embryonic stem cells in vitro.

Tadao Atsumi, Mariko Nagayoshi, Hiroko Anzai, Yoji Ikawa

Abstract read
PubMed Publisher
In one paragraph

Article in Development, growth & differentiation, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tadao AtsumiLaboratory of Molecular Oncology, Tsukuba Life Science Center, The Institute of Physical and Chemical Research, 3-1-1, Koyadai, Tsukuba 305, Japan.
Mariko NagayoshiLaboratory of Molecular Oncology, Tsukuba Life Science Center, The Institute of Physical and Chemical Research, 3-1-1, Koyadai, Tsukuba 305, Japan.
Hiroko AnzaiLaboratory of Molecular Oncology, Tsukuba Life Science Center, The Institute of Physical and Chemical Research, 3-1-1, Koyadai, Tsukuba 305, Japan.
Yoji IkawaLaboratory of Molecular Oncology, Tsukuba Life Science Center, The Institute of Physical and Chemical Research, 3-1-1, Koyadai, Tsukuba 305, Japan.
University of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryonic stem (ES) cells effectively differentiated into primitive erythroid/mesodermal cells when grown in the absence of both a feeder layer and leukemia inhibitory factor (LIF). The formation of a three-dimensional structure, exogenous mesoderm induction factors and exogenous hematopoietic growth factors were not essential for their differentiation. Primitive erythroid cells were first detected on day 5 in the differentiation-permissive cultures. Differentiation into other mesodermal cells was always preceded by that into primitive erythroid cells. Precursor cells of erythroid cells but of other hematoid cells were also detected in this system. This model system is useful for studying the early steps of mesoderm formation in mouse embryogenesis.

Indexed as

blood islandembryonic stem cellLIFmesodermal differentiationprimitive erythroid cell

Identifiers

PMID37282308
OpenAlexW2071713859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.