ReviewDevelopment, growth & differentiation1996
The ascidian embryo: An experimental system for studying genetic circuitry for embryonic cell specification and morphogenesis.
Review in Development, growth & differentiation, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 30 citations in OpenAlex.
- Cross-coupling between voltage-dependent Ca2+ channels and ryanodine receptors in developing ascidian muscle blastomeres.The Journal of physiology · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ascidians have served as an appropriate experimental system in developmental biology for more than a century. The fertilized egg develops quickly into a tadpole larva, which consists of a small number of tissues including the epidermis, central nervous system with two sensory organs, nerve cord, endoderm, mesenchyme, notochord and muscle. Lineage of these embryonic cells is completely described up to the gastrula stage. These features of the ascidian embryo provide an opportunity to study the mechanisms underlying the differentiation of tissues in development. To understand the molecular basis of ascidian embryogenesis, cloning of various genes has been performed, including those that exhibit a lineage-associated expression pattern and those encoding transcription factors, which are expected to be involved in differentiation of tissues, lineage specification, axis formation and regionalization in developmental fields. Here, we present recent advances in the isolation and characterization of these genes. We emphasize the advantages of the ascidian embryo as an experimental system to study genetic circuitries that are required for cellular differentiation and morphogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.