ReviewDevelopment, growth & differentiation1996
Amphibian metamorphosis: An exquisite model for hormonal regulation of postembryonic development in vertebrates.
Review in Development, growth & differentiation, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 36 citations in OpenAlex.
- Mind Everywhere: A Framework for Conceptualizing Goal-Directedness in Biology and Other Domains-Part One.Biological theory · 2026Article
- Pregametogenesis: The Earliest Stages of Gonad and Germline Differentiation in Anuran Amphibians.Biology · 2024Review
- Hsp90 and hepatobiliary transformation during sea lamprey metamorphosis.BMC developmental biology · 2015Article
- Quantitative Proteomics of an Amphibian Pathogen, Batrachochytrium dendrobatidis, following Exposure to Thyroid Hormone.PloS one · 2015Article
- Review
- Minireview: Defining the roles of the iodothyronine deiodinases: current concepts and challenges.Endocrinology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metamorphosis in invertebrates and vertebrates is an ideal model for studying mechanisms of postembryonic development regulated by external signals. Amphibian metamorphosis shares many similarities with mammalian development in the perinatal period. The precocious induction in vivo and in culture of amphibian metamorphosis by exogenous thyroid hormones and its retardation or inhibition by prolactin, have allowed the analysis of such characteristic features of postembryonic development as morphogenesis, tissue remodelling, gene reprogramming and programmed cell death. Recent studies on metamorphosis have revealed the important role played by such processes as auto- and cross-regulation of hormone receptor genes and by cell death or apoptosis, as in the maturation of the central nervous system, tissue restructuring and organolysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.