Evidence map›Paper›PMID 37280776›Full record

ArticleJournal of microbiology and biotechnology2023

Anti-Inflammatory Response in TNFα/IFNγ-Induced HaCaT Keratinocytes and Probiotic Properties of

Ji Yeon Lee, Jeong-Yong Park, Yulah Jeong, Chang-Ho Kang

Open access · greenAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Anti-Inflammatory Activities of Baobab Fruit Extracts in TNF-Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Effects of Canine-DerivedAnimals : an open access journal from MDPI · 2026
    Article
  7. Article
  8. Article
  9. Anti-Inflammation and Anti-Hypersensitivity Effects ofPreventive nutrition and food science · 2025
    Article
  10. Article
  11. Article
  12. The Effect ofMicroorganisms · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Nutrients · 2024
    Article
  17. Probiotic, Postbiotic, and Paraprobiotic Effects ofFoods (Basel, Switzerland) · 2024
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ji Yeon LeeMediogen Co., Ltd., Jecheon 27159, Republic of Korea.
Jeong-Yong ParkMediogen Co., Ltd., Jecheon 27159, Republic of Korea.
Yulah JeongMediogen Co., Ltd., Jecheon 27159, Republic of Korea.
Chang-Ho KangMediogen Co., Ltd., Jecheon 27159, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic inflammatory disease caused by immune dysregulation. Meanwhile, the supernatant of lactic acid bacteria (SL) was recently reported to have anti-inflammatory effects. In addition, HaCaT keratinocytes stimulated by tumor necrosis factor alpha (TNF-α) and interferon gamma (IFN-γ) are widely used for studying AD-like responses. In this study, we evaluated the anti-inflammatory effects of SL from lactic acid bacteria (LAB) on TNF-α/IFN-γ-induced HaCaT keratinocytes, and then we investigated the strains' probiotic properties. SL was noncytotoxic and regulated chemokines (macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC)) and cytokines (interleukin (IL)-4, IL-5, IL-25, and IL-33) in TNF-α/IFN-γ-induced HaCaT keratinocytes. SL from

Indexed as

Dermatitis, AtopicLactococcus lactisAnti-Inflammatory AgentsHumansInterferon-gammaKeratinocytesLacticaseibacillusNF-kappa BTumor Necrosis Factor-alphaAnti-Inflammatory AgentsInterferon-gammaNF-kappa BTumor Necrosis Factor-alphaAnti‐inflammationcell‐free supernatantkeratinocyteslactic acid bacteriaprobiotics

Identifiers

PMID37280776
PMCPMC10468673
OpenAlexW4379599896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.