Evidence map›Paper›PMID 37280708›Full record

ArticleVeterinary research2023

Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur.

Sofie Rutjens, Nick Vereecke, Jannes Sauer, Siska Croubels, Mathias Devreese

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sofie RutjensDepartment of Pathobiology, Pharmacology and Zoological Medicine, Laboratory of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820, Merelbeke, Belgium.ORCID http://orcid.org/0000-0003-1526-1492
Nick VereeckePathoSense BV, 2500, Lier, Belgium.
Jannes SauerPathoSense BV, 2500, Lier, Belgium.
Siska CroubelsDepartment of Pathobiology, Pharmacology and Zoological Medicine, Laboratory of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820, Merelbeke, Belgium.
Mathias DevreeseDepartment of Pathobiology, Pharmacology and Zoological Medicine, Laboratory of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820, Merelbeke, Belgium. Mathias.Devreese@UGent.be.
Ghent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cephalosporins are licensed for treatment of severe bacterial infections in different species. However, the effect of these antimicrobials on the fecal microbiome and potential spread of resistance-associated genes causes great concern. This highlights the need to understand the impact of cephalosporins on the porcine fecal microbiome and resistome. A combination of long-read 16S rRNA gene and shotgun metagenomic sequencing was applied to investigate the effect of conventional treatment with either ceftiofur (3 mg.kg

Indexed as

Anti-Infective AgentsGastrointestinal MicrobiomeAnimalsAnti-Bacterial AgentsCephalosporinsEscherichia coliFecesRNA, Ribosomal, 16SSwineAnti-Bacterial AgentsAnti-Infective AgentscefquinomeceftiofurCephalosporinsRNA, Ribosomal, 16S16S rRNA sequencingARGsgut microbiomemetagenomicsporcine fecesresistomeshotgun sequencingVeterinary cephalosporins

Identifiers

PMID37280708
PMCPMC10242799
OpenAlexW4379537749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.