Evidence map›Paper›PMID 37280620›Full record

ArticleBMC biology2023

The genomes of Vischeria oleaginous microalgae shed light on the molecular basis of hyper-accumulation of lipids.

Baoyan Gao, Meng Xu, Dai Shan, Chi Zhang, Yulan Yang, Zhensheng Dong, Hu Zhang, Boping Han, Luodong Huang, Chengwu Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Complete mitochondrial genome of an oleaginous microalgaMitochondrial DNA. Part B, Resources · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Baoyan Gao *Department of Ecology & Research Center for Hydrobiology, Jinan University, Guangzhou, 510632, China.ORCID 0000-0003-1293-0451
Meng Xu *Department of Ecology & Research Center for Hydrobiology, Jinan University, Guangzhou, 510632, China.
Dai Shan *BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Chi Zhang *BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Yulan YangBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Zhensheng DongBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Hu ZhangDepartment of Ecology & Research Center for Hydrobiology, Jinan University, Guangzhou, 510632, China.
Boping HanDepartment of Ecology & Research Center for Hydrobiology, Jinan University, Guangzhou, 510632, China. tbphan@jnu.edu.cn.
Luodong HuangDepartment of Ecology & Research Center for Hydrobiology, Jinan University, Guangzhou, 510632, China. ynhuangld@gxu.edu.cn.
Chengwu ZhangDepartment of Ecology & Research Center for Hydrobiology, Jinan University, Guangzhou, 510632, China. tzhangcw@jnu.edu.cn.
BGI Group (China) · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the urgent need to reduce carbon emissions, and the dwindling reserves of easily exploitable fossil fuel, microalgae-based biofuels that can be used for transport systems and CO

resultsA whole-genome duplication (WGD) event was revealed in V. sp. CAUP H4302, which is a rare event in unicellular microalgae. Comparative genomic analyses showed that a battery of genes encoding pivotal enzymes involved in fatty acids and triacylglycerol biosynthesis, storage polysaccharide hydrolysis, and nitrogen and amino acid-related metabolisms are expanded in the genus Vischeria or only in V. sp. CAUP H4302. The most highlighted is the expansion of cyanate lyase genes in the genus Vischeria, which may enhance their detoxification ability against the toxic cyanate by decomposing cyanate to NH

conclusionsThis study presents a WGD event in microalgae, providing new insights into the genetic and regulatory mechanism underpinning hyper-accumulation of lipids and offering potentially valuable targets for future improvements in oleaginous microalgae by metabolic engineering.

Indexed as

LipidsMicroalgaeBiomassCarbon DioxideFatty AcidsNitrogenCarbon DioxideFatty AcidsLipidsNitrogenCyanate lyaseGenome analysisTriacylglycerolsVischeria sp. CAUP H4302Vischeria stellataWhole-genome duplication

Identifiers

PMID37280620
PMCPMC10245428
OpenAlexW4379511039

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.