ArticleBMC endocrine disorders2023
Association between metabolic syndrome and stroke: a population based cohort study.
Article in BMC endocrine disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 28 citations in OpenAlex.
- Syndemic analysis of stroke in Indonesia.The Lancet regional health. Western Pacific · 2026Article
- Gut Microbiota and Stroke: New Insights into the Gut-Brain-Vascular Axis.Current atherosclerosis reports · 2026Review
- A Blurred Vision of Health: Metabolic Syndrome as a Risk Factor for Glaucoma in a Large Taiwanese Population Study.International journal of medical sciences · 2026Article
- Association between stress hyperglycemic ratio and stroke in older people with metabolic syndrome: a prospective cohort study from UK Biobank.Frontiers in endocrinology · 2026Article
- Metabolic syndrome severity and all-cause mortality in the CLHLS biomarker subsample of older Chinese adults.Frontiers in public health · 2026Article
- The association between the ZJU index and short-term prognosis in patients with acute ischemic stroke: a cohort study.Frontiers in endocrinology · 2026Article
- Dynamic Changes in Metabolic Syndrome Scores and New-Onset Stroke Risk in Middle-Aged and Older Adults: A Nationwide Prospective Cohort Study in China Aligned With Predictive, Preventive, and Personalized Medicine.Journal of the American Heart Association · 2025Article
- Prevalence of the Metabolic Syndrome and its Associated Factors among Hospital Workers at a Rwandan Provincial Hospital: A Cross-Sectional Study.Rwanda journal of medicine and health sciences · 2025Article
- Review
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- Association of weight-adjusted-waist index with all-cause and cardiovascular mortality in hypertension: a prospective cohort study.BMC public health · 2025Article
- Comparison of Ischemic Stroke Outcomes in Patients With and Without Metabolic Syndrome: A Systematic Review.Cureus · 2025Review
- The Association of Cardiometabolic Risk Factors in Parent-Child Dyads in Guam: Pacific Islands Cohort on Cardiometabolic Health Study.International journal of environmental research and public health · 2025Article
- The association between noodle consumption and metabolic syndrome in Korean adults.Asia Pacific journal of clinical nutrition · 2025Article
- Article
- Evaluating machine learning models for stroke prediction based on clinical variables.Frontiers in neurology · 2025Article
- The interplay between metabolic health factors and stroke incidence in aging populations.Frontiers in endocrinology · 2025Article
- Association Between Sleep Duration and Related Risk Factors with Metabolic Syndrome: A Systematic Review and Meta-analysis.International journal of preventive medicine · 2025Review
- White matter microstructural damage and its effect on cognitive impairment in patients with metabolic syndrome and cerebral small vessel disease.Frontiers in neurology · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both metabolic syndrome (MetS) and stroke are associated with increased risk of mortality. Here, we aimed to assess the prevalence of MetS among adults using three definitions (Adult Treatment Panel III (ATP-III), International Diabetes Federation (IDF) and IDF ethnic specific cut-off for Iranian criteria) and its association with stroke. We performed a cross-sectional study of a total of 9991 adult participants of Rafsanjan Cohort Study (RCS), as part of the Prospective epidemiological research studies in Iran (PERSIAN cohort study). The MetS prevalence was evaluated in participants according to the different criteria. Multivariate logistic regression analyses were conducted to assess the association between three definitions of MetS with stroke. We found that MetS was significantly associated with higher odds of stroke according to NCEP-ATP III (odds ratio (OR): 1.89, 95% confidence interval (CI) 1.30-2.74), international IDF (OR:1.66, 95% CI: 1.15-2.40) and Iranian IDF (OR:1.48, 95% CI: 1.04-2.09) after adjusted for variables confounders. Furthermore, after adjustment, in receiver operating characteristic (ROC) curve, the AUROC was 0.79 (95% CI = 0.75-0.82), 0.78(95% CI = 0.74-0.82) and 0.78(95% CI = 0.74-0.81) for presence of MetS according to NCEP-ATP III, international IDF and Iranian IDF, respectively. ROC analyses revealed that all of these three criteria for MetS are "moderately accurate" for the identification of increased stroke risk.In conclusion, our results showed that MetS was associated with increased odds of stroke. Our findings implicate the importance of early identification, treatment, and ultimately prevention of the metabolic syndrome.
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